Neurological and survival outcomes after surgical management of subaxial cervical spine metastases

Spine
Wonik Cho, Ung-Kyu Chang

Abstract

A clinical retrospective study. To investigate the clinical outcomes of surgery for cervical spine metastasis and identify factors affecting survival and neurological result. Metastatic disease in the cervical spine is known to be a poorer prognosis than in thoracic and lumbar regions. Few reports focused on cervical spine metastasis are available. A retrospective analysis of medical records and radiological data was performed on 46 patients who underwent surgical treatment due to cervical spine metastasis from 2000 to 2010. The incidence of cervical metastasis, overall survival, progression-free survival, and neurological and pain outcomes were analyzed. In addition, factors affecting survival, local recurrence, and neurological and pain outcomes among the 46 study subjects were analyzed. These factors included; age, sex, primary tumor growth rate, preoperative disease-progression status (expressed with Tomita score), irradiation, timing of irradiation, postoperative adjuvant therapy, time of diagnosis of spinal metastasis, cord compression or foraminal invasion on magnetic resonance image, preoperative neurological status, and preoperative pain level. The incidence of cervical metastasis was 17.3%. Mean postoperative overall ...Continue Reading

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