Neurological aspects of areca and betel chewing

Addiction Biology
Nai-Shin Chu

Abstract

Betel quid chewing has been claimed to produce a sense of well-being, euphoria, warm sensation of the body, sweating, salivation, palpitation, heightened alertness and increased capacity to work. These effects suggest that betel quid chewing affects predominantly the central and autonomic nervous systems. Several studies have been conducted to elucidate the central and autonomic effects of betel quid chewing. The results are: (1) betel quid chewing increased the heart rate with onset within 2 minutes, maximal effect within 4-6 minutes and an average duration of 16.8 minutes. The cardio-acceleratory response was more prominent for fresh and occasional chewers than for habitual chewers; (2) betel quid chewing increased the skin temperature with onset and duration similar to a cardio-acceleratory response. The hyperthermic effect was abolished by atropine and partly inhibited by propranolol. (3) Betel quid chewing had no effect on simple reaction time but shortened the choice reaction time. (4) Betel quid chewing produced widespread cortical desynchronization of EEG. (5) Chewing of one or two betel quids attenuated the sympathetic skin response while continued consumption of more than two betel quids affected the RR interval varia...Continue Reading

References

Oct 1, 1978·Neurology·J G NuttT N Chase
Aug 1, 1979·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·B G Burton-Bradley
Aug 1, 1976·Circulation Research·C J MathiasJ M Spalding
Mar 1, 1985·The Australian and New Zealand Journal of Psychiatry·J Cawte
Jan 1, 1981·The British Journal of Psychiatry : the Journal of Mental Science·J E ChristieA I Glen
Apr 1, 1995·Journal of Psychoactive Drugs·N S Chu
Feb 1, 1994·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·M Y KuoL J Hahn
Jan 1, 1993·Cardiovascular Research·A L Tucker, J Linden
Feb 1, 1997·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·E C Chu, N S Chu
Apr 1, 1955·A.M.A. Archives of Neurology and Psychiatry·F RINALDI, H E HIMWICH
Jan 1, 1945·Acta Pharmacologica Et Toxicologica·U S VON EULER, B DOMEIJ

❮ Previous
Next ❯

Citations

Aug 23, 2012·PloS One·Rajeshwar N SharanKamlesh Asotra
Nov 10, 2013·International Journal of Molecular Sciences·Szu-Chia ChenHung-Chun Chen
Sep 19, 2012·Indian Journal of Medical and Paediatric Oncology : Official Journal of Indian Society of Medical & Paediatric Oncology·Gunjan ShahSagar Vaishampayan
Sep 22, 2012·The British Journal of Psychiatry : the Journal of Mental Science·Chien-Hung LeeYing-Chin Ko
Feb 20, 2014·International Journal of Epidemiology·Tyler R McClintockYu Chen
Nov 10, 2006·Community Dentistry and Oral Epidemiology·Ching-Shiun LaiChi-Cheng Tsai
Jul 30, 2014·BMC Public Health·Fu-Li ChenMin-Chien Tsai
Mar 1, 2008·Journal of Psychopharmacology·S-S Chiou, C-D Kuo
Aug 7, 2010·Scandinavian Journal of Public Health·Fawad JavedKhalid Almas
Nov 17, 2017·Social Psychiatry and Psychiatric Epidemiology·Tzu-Yu LinKuang-Hung Hsu
Mar 20, 2002·Addiction Biology·A Winstock
Dec 7, 2017·Frontiers in Psychiatry·Xiaojun HuangZhening Liu
Jan 30, 2018·BioMed Research International·Ping-Ho ChenKa-Wo Lee
Jul 18, 2018·PloS One·Chen-Yi LeeYong-Yuan Chang
Sep 22, 2018·Community Dentistry and Oral Epidemiology·Irene Tamí-MauryEllen R Gritz
Mar 25, 2005·Journal of Immigrant Health·Jyotsna Changrani, Francesca Gany
Jul 1, 2009·Human Psychopharmacology·Christopher J EdgarKeith A Wesnes
Apr 24, 2010·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Stephen CoxHans Zoellner
Mar 15, 2006·Urological Research·Siân E AllenWilliam G Robertson
Oct 24, 2017·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Nicole A HorensteinRoger L Papke
May 30, 2016·Psychopharmacology·Meng-Chun ChiuMing-Chou Ho
Oct 7, 2011·Attention, Perception & Psychophysics·Ming-Chou Ho, Chin-Kun Wang
Apr 28, 2011·Addiction Biology·Ping-Ho ChenYing-Chin Ko
May 21, 2011·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Cheng-Hsu WangKun-Yun Yeh
Feb 22, 2012·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·F J MateenR E Black
Aug 22, 2017·Frontiers in Psychiatry·Fulai YuanWeihua Liao
Apr 17, 2007·Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology·Indraneel SahaB R Maiti
Jun 23, 2020·Substance Use & Misuse·Kinley Wangdi, Tshering Jamtsho
Jun 10, 2006·The American Journal of Clinical Nutrition·Jinn-Yuh GuhHung-Chun Chen
May 11, 2007·The American Journal of Clinical Nutrition·Jinn-Yuh GuhLea-Yea Chuang
Oct 28, 2017·Frontiers in Psychiatry·Fulai YuanCanhua Jiang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.