Neurological complications of vasculitis

Annals of Neurology
P M Moore, T R Cupps

Abstract

The vasculitides are a group of disorders that include the polyarteritis nodosa group of systemic necrotizing vasculitides, hypersensitivity vasculitis, Wegener's granulomatosis, lymphomatoid granulomatosis, giant cell arteritis, Behçet's disease, and isolated angiitis of the central nervous system. Classification is based on clinical, angiographic, and histological features. The frequency and distribution of neurological involvement vary with the underlying disorder and may provide the initial symptoms. Polyarteritis nodosa and Wegener's granulomatosis may affect both the central and peripheral nervous systems, whereas isolated angiitis of the central nervous system and Behçet's disease affect the central nervous system alone. Neurological dysfunction occurs in 80% of patients with polyarteritis nodosa and fewer than 10% of patients with hypersensitivity vasculitis. The mechanism of neurological dysfunction in the vasculitides is tissue ischemia. The clinical effects of ischemia vary, and symptoms may be transient or prolonged. Mononeuritis multiplex, polyneuropathy, and stroke are frequent complications, but encephalopathies, cranial neuropathies, and brachial plexopathies are seen as well. The occurrence of symptoms late in ...Continue Reading

References

May 1, 1996·Cancer·J E NaschitzL M Lev
Dec 1, 1990·Annals of Neurology·P HumphreysA M Galaburda
Feb 1, 1990·Muscle & Nerve·A Ropert, S Metral
Dec 1, 1989·Journal of Neurology·T OhtakeH Tanabe
Jan 1, 1996·Springer Seminars in Immunopathology·Gérard Said
Apr 1, 1997·Italian Journal of Neurological Sciences·F TraversoB Fazio
Sep 1, 1996·Digestive Diseases and Sciences·C DejacoA Gangl
Apr 1, 1987·Italian Journal of Neurological Sciences·G PavesiA Marbini
Feb 5, 2005·European Journal of Nuclear Medicine and Molecular Imaging·Tarik BelhocinePatrick Flamen
Apr 5, 2005·Journal of Neurology·Gérard Said, Catherine Lacroix
Oct 1, 1996·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·T S Ha, S H Cha
Nov 23, 2006·Clinical Rheumatology·R Peshin, D O'Gradaigh
Jan 20, 2007·Clinical Rheumatology·Ozan OzkayaHaydar Ali Taşdemir
Sep 1, 1988·Journal of the Neurological Sciences·H HeiskalaM Haltia
Nov 1, 1989·Journal of the Neurological Sciences·P M Moore
Dec 1, 1990·Journal of the Neurological Sciences·P K PanegyresA J Bourne
Jan 1, 1992·Clinical Neurology and Neurosurgery·R TopalogluA Oner
Nov 1, 1994·Clinical Neurology and Neurosurgery·V FetoniF Girotti
Feb 1, 1996·Clinical Neurology and Neurosurgery·E M JöbgesT F Münte
Apr 1, 1996·Disease-a-month : DM·N Futrell, C H Millikan
Nov 7, 2002·Critical Care Clinics·Rula A Hajj-AliAlejandro C Arroliga
Mar 18, 2003·Joint, Bone, Spine : Revue Du Rhumatisme·Constantin GomesAlain Saraux
Jul 1, 1987·Annals of Surgery·L M TaylorJ M Porter
Mar 10, 2005·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Mário Luiz Ribeiro MonteiroCláudia Costa Leite
Dec 18, 2004·Current Opinion in Rheumatology·Christian Pagnoux, Loïc Guillevin
Apr 30, 2004·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Ana Paula De Carvalho Panzeri CarlottiDaniel Chang
Aug 1, 1991·Journal of Internal Medicine·C BisgårdK Juel
Sep 16, 2009·Neuropathology : Official Journal of the Japanese Society of Neuropathology·Orestes E SolisHarry V Vinters
Jun 1, 1992·Australian and New Zealand Journal of Medicine·P L Silbert, E G Stewart-Wynne
Apr 1, 1993·Acta Neurologica Scandinavica·A EngelhardtB Neundörfer

Citations

Jan 1, 1976·Medicine·J DuffyK W Min
Jan 1, 1976·Japanese Heart Journal·K AbeH Aoyagi
Jan 1, 1977·American Heart Journal·E Lupi-HerreraJ E Vela
May 1, 1977·Circulation·A TakeshitaM Nakamura
Feb 1, 1979·Seminars in Arthritis and Rheumatism·R L TraversG R Hughes
Dec 1, 1979·The American Journal of Medicine·E S LeibH E Paulus
Mar 24, 1979·Lancet·G R HughesI Jamieson
Jun 1, 1975·Neurology·C R StaffordH B Spector
Oct 1, 1978·Journal of Neurochemistry·G E GibsonJ P Blass
May 1, 1979·Annals of Neurology·P C JohnsonJ F Laguna
Apr 1, 1975·Archives of Neurology·M Ramos, T I Mandybur
May 1, 1979·Seminars in Arthritis and Rheumatism·T ShimizuK Hayashi
Jan 1, 1979·Archives of Neurology·P Watson
Sep 1, 1979·Stroke; a Journal of Cerebral Circulation·E EsteyJ Ransohoff
Dec 1, 1977·Neurology·F KozinG C Bernhard
Oct 1, 1979·Neurology·G Selby, G L Walker
Dec 1, 1977·Archives of Neurology·E KokmenM R Abell
Nov 1, 1977·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·P WatsonJ Deck
Feb 1, 1978·Annals of Internal Medicine·K A HustonL R Elveback
Jun 1, 1978·The Journal of Nervous and Mental Disease·J W CochranM P Kelly
Apr 1, 1978·Annals of Neurology·W I RosenblumH F Young
Oct 5, 1978·The New England Journal of Medicine·B F Haynes, A S Fauci
Sep 1, 1978·Arthritis and Rheumatism·L F LayferH E Golden
Jan 1, 1979·Cancer·A L KatzensteinA A Liebow
Jun 1, 1977·Brain : a Journal of Neurology·M E BarricksI S Levy
Oct 1, 1977·Archives of Neurology·T KansuN J Schatz
Oct 1, 1977·The Journal of Pediatrics·A V MoorthyT Groshong
Dec 1, 1975·Annals of Internal Medicine·R G KleinS G Sheps
Jan 1, 1971·Journal of Neurochemistry·S Ochs, D Hollingsworth
Apr 1, 1969·Annals of Internal Medicine·H B Kaltreider, N Talal
Nov 5, 1970·The New England Journal of Medicine·B P CitronB J Haverback
Oct 1, 1974·Annals of Internal Medicine·S M WolffD C Dale
Jan 1, 1973·Advances in Immunology·C G Cochrane, D Koffler
Dec 1, 1972·Human Pathology·A A LiebowP J Friedman

Related Concepts

Vasculitis
Polyneuropathy
Ischemia
Neurologic Manifestations
Cyclophosphamide
Decreased Immunologic Activity [PE]
Infantile Polyarteritis
Churg-Strauss Syndrome
Structure of Sural Nerve
Granulomatosis

Related Feeds

Aortic Coarctation

Aortic coarctation is a congenital condition characterized by narrowing of the aorta. Discover the latest research on this disease here.