Neurological outcome of childhood brain tumor survivors.

Journal of Neuro-oncology
Sari PietiläA Mäkipernaa

Abstract

We assessed neurological and neurocognitive outcome in childhood brain tumor survivors. Altogether, 75 out of 80 brain tumor survivors diagnosed below 17 years between 1983 and 1997; and treated in Tampere University Hospital, Finland, were invited to participate in this population-based cross-sectional study. Fifty-two (69%) participated [mean age 14.2 (3.8-28.7) years, mean follow-up 7.5 (1.5-15.1) years]. Neurological status was abnormal in 69% cases. All were ambulatory, but only 50% showed normal motor function. Twenty-nine percent showed clumsiness/mild asymmetry and 21% hemiparesis. One suffered from intractable epilepsy. According to structured interview, 87% coped normally in daily living. Median full-scale IQ was 85 (39-110) in 21 6-16 year olds (70%); in 29% IQ was <70. Thirty of the 44 school-aged subjects attended school with normal syllabus and 32% needed special education. Six of the 16 patients over 18 years of age were working. Regarding quality of life, 38% were active without disability, 33% active with mild disability, 21% were partially disabled, but capable of self-care, and 8% had severe disability, being incapable of self-care. Supratentorial/hemispheric tumor location, tumor reoperations, shunt revision...Continue Reading

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Citations

Feb 28, 2015·Journal of Neurosurgery. Pediatrics·Cydni N WilliamsSusan L Bratton
Aug 28, 2013·Current Treatment Options in Neurology·Kevin C De Braganca, Roger J Packer
Apr 29, 2014·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Bledi BrahimajFrancesco T Mangano
Apr 12, 2018·Journal of Adolescent and Young Adult Oncology·Kaspar Jessen PedersenHanne Baekgaard Larsen
Jun 7, 2018·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Kevin R KrullShelli R Kesler
Mar 6, 2016·Journal of Child Neurology·Sari PietiläAnne Mäkipernaa
Dec 17, 2016·Pediatric Physical Therapy : the Official Publication of the Section on Pediatrics of the American Physical Therapy Association·Jessica SparrowKirsten K Ness
Aug 25, 2018·Brain Connectivity·Michelle E Fox, Tricia Z King
Nov 16, 2013·Annals of Rehabilitation Medicine·Dae Hwan ParkYoon Bum Song
Jan 17, 2017·The International Journal of Neuroscience·Min Ho ChunMin Cheol Chang
Apr 15, 2016·Journal of Adolescent and Young Adult Oncology·Tami D JohnDaniela A Bota
Jan 28, 2020·Seminars in Oncology Nursing·Lynn TannerJessica Sparrow
Apr 23, 2021·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Nicholas S PhillipsNicole J Ullrich
May 23, 2021·Pediatric Blood & Cancer·Anne Sophie Lind HelligsoeHenrik Hasle

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