Neuromagnetic Beta-Band Oscillations during Motor Imitation in Youth with Autism

Autism Research and Treatment
Isabelle BuardD C Rojas

Abstract

Children with ASD often exhibit early difficulties with action imitation, possibly due to low-level sensory or motor impairments. Impaired cortical rhythms have been demonstrated in adults with ASD during motor imitation. While those oscillations reflect an age-dependent process, they have not been fully investigated in youth with ASD. We collected magnetoencephalography data to examine patterns of oscillatory activity in the mu (8-13 Hz) and beta frequency (15-30 Hz) range in 14 adolescents with and 14 adolescents without ASD during a fine motor imitation task. Typically developing adolescents exhibited adult-like patterns of motor signals, e.g., event-related beta and mu desynchronization (ERD) before and during the movement and a postmovement beta rebound (PMBR) after the movement. In contrast, those with ASD exhibited stronger beta and mu-ERD and reduced PMBR. Behavioral performance was similar between groups despite differences in motor cortical oscillations. Finally, we observed age-related increases in PBMR and beta-ERD in the typically developing children, but this correlation was not present in the autism group. These results suggest reduced inhibitory drive in cortical rhythms in youth with autism during intact motor ...Continue Reading

References

Mar 1, 1985·Electroencephalography and Clinical Neurophysiology·G BarrettR Neshige
Nov 1, 1988·Archives of Disease in Childhood·T H Koh, J A Eyre
Oct 1, 1973·Developmental Medicine and Child Neurology·M B Denckla
Mar 1, 1981·Electroencephalography and Clinical Neurophysiology·G Pfurtscheller
Aug 1, 1983·Developmental Medicine and Child Neurology·P H WolffC Cohen
Oct 1, 1981·Archives of Neurology·J A VilenskyR G Maurer
Jun 1, 1997·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·R HariM Helle
Sep 1, 1997·IEEE Transactions on Bio-medical Engineering·B D Van VeenA Suzuki
Feb 19, 1998·Journal of Abnormal Child Psychology·W L StoneC D Littleford
Nov 27, 1999·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·G Pfurtscheller, F H Lopes da Silva
Jan 5, 2000·Neuroreport·S AvikainenR Hari
May 3, 2000·Brain Topography·D J McFarlandJ R Wolpaw
Jan 22, 2002·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Rumyana Kristeva-FeigeCarl-Hermann Lücking
Sep 28, 2002·Development and Psychopathology·Geraldine DawsonTodd Richards
Nov 11, 2003·Genes, Brain, and Behavior·J L R Rubenstein, M M Merzenich
Jan 13, 2004·Journal of Autism and Developmental Disorders·Brooke IngersollQuy H Tran
Jul 22, 2004·Journal of Autism and Developmental Disorders·Justin H G WilliamsTulika Singh
Sep 24, 2004·Brain Topography·Karsten HoechstetterMichael Scherg
Mar 23, 2005·Neuroscience Letters·G PfurtschellerF Lopes da Silva
Jun 28, 2005·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Louise M F DoylePeter Brown
Jul 5, 2005·Brain Research. Cognitive Brain Research·Lindsay M ObermanJaime A Pineda
Jan 31, 2006·International Review of Neurobiology·Arjan Hillebrand, Gareth R Barnes
Nov 23, 2006·Nature Reviews. Neuroscience·Marco Iacoboni, Mirella Dapretto
Dec 21, 2006·Journal of Autism and Developmental Disorders·Katherine GothamCatherine Lord
May 5, 2007·Autism : the International Journal of Research and Practice·Marleen VanvuchelenWilly De Weerdt
Aug 1, 2007·Journal of Autism and Developmental Disorders·Heidi Stieglitz HamSara Swanson
Mar 4, 2008·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Joëlle MartineauCatherine Barthelemy
Apr 22, 2008·NeuroImage·Tonio BallAndreas Schulze-Bonhage
May 20, 2008·Nature Neuroscience·Anne K ChurchlandMichael N Shadlen
Sep 30, 2008·Journal of Autism and Developmental Disorders·S Hossein FatemiPaul D Thuras
Sep 29, 2009·Brain Research·Ruth RaymaekersHerbert Roeyers
Dec 25, 2009·Journal of Child Neurology·Kyle J SteinmanMartha B Denckla
Mar 3, 2010·Journal of Autism and Developmental Disorders·Kimberly A FournierJames H Cauraugh

❮ Previous
Next ❯

Citations

Jan 29, 2021·Frontiers in Human Neuroscience·Julia C BassoRachel Rugh

❮ Previous
Next ❯

Methods Mentioned

BETA
Chip
chips

Software Mentioned

MEGIS
BESA MRI
prime
Brain Electrical Source Analysis ( BESA ) MRI
BESA Research
BESA

Related Concepts

Related Feeds

Adenoma, Islet Cell

Islet Cell Adenoma arises in the islet cells, which are insulin producing cells of the pancreas. These tumors can be either malignant or benign. Discover the latest research on Islet Cell Adenoma here.

Autism: Treatment Targets

The absence of effective treatments for autism are due to the high clinical and genetic heterogeneity between affected individuals, restricted knowledge of the underlying pathophysiological mechanisms, and the lack of reliable diagnostic biomarkers. Identification of more homogenous biological subgroups is therefore essential for the development of novel treatments based on the molecular mechanisms underpinning autism and autism spectrum disorders. Find the latest research on autism treatment targets here.

Autism

Autism spectrum disorder is associated with challenges with social skills, repetitive behaviors, and often accompanied by sensory sensitivities and medical issues. Here is the latest research on autism.