Neuromolecular Regulation of Aggression Differs by Social Role during Joint Territory Defense

Integrative and Comparative Biology
C A WeitekampHans A Hofmann

Abstract

In response to a territory intrusion, neighboring males of the African cichlid fish Astatotilapia burtoni engage in aggressive joint territory defense in a manner that depends on their social role. Here, we examine the possible function of several neuroendocrine and neuromodulator pathways previously implicated in the regulation of complex social behavior. We find that the neuromolecular regulation of aggression during joint territory defense is very much dependent on an individual's role in this context. In neighbors but not in residents, aggression is correlated to gene expression in the medial part of the dorsal telencephalon (area Dm), the putative homolog to the mammalian basolateral amygdala. This correlation is strikingly high for expression of the serotonin receptor 5-HT2c, suggesting the serotonin system is important in regulating context-dependent behavior. Furthermore, by examining candidate gene expression co-variance patterns in area Dm and in the lateral part of the dorsal telencephalon (area Dl), the putative homolog to the mammalian hippocampus, we identify two main patterns: gene expression is co-regulated within, but not across, brain regions, and co-regulation is synergistic rather than antagonistic. Our resu...Continue Reading

References

Jul 1, 1996·Physiology & Behavior·H MaaswinkelB M Spruijt
Feb 18, 1998·Current Opinion in Neurobiology·D H Edwards, E A Kravitz
Dec 20, 1999·Behavioural Brain Research·E M HullJ Moses
Mar 17, 2001·Nature Reviews. Neuroscience·H Eichenbaum
Feb 16, 2002·Methods : a Companion to Methods in Enzymology·K J Livak, T D Schmittgen
May 6, 2003·Proceedings of the National Academy of Sciences of the United States of America·Elena CholerisSonoko Ogawa
Aug 2, 2005·Physiological and Biochemical Zoology : PBZ·Cliff H SummersNeil Greenberg
Aug 24, 2005·The European Journal of Neuroscience·Clémentine VignalNicolas Mathevon
Oct 12, 2005·PLoS Biology·Sabrina S BurmeisterRussell D Fernald
Oct 20, 2006·Pharmacology & Therapeutics·K D Alex, E A Pehek
Jan 26, 2007·Nature·Logan GrosenickRussell D Fernald
Feb 27, 2007·Physiology & Behavior·Alison M BellSvante Winberg
Mar 16, 2007·Proceedings of the National Academy of Sciences of the United States of America·Elena CholerisDonald W Pfaff
Jul 8, 2008·Journal of Neuroendocrinology·K J Kovács
Nov 8, 2008·Science·Gene E RobinsonDavid F Clayton
Jul 18, 2009·General and Comparative Endocrinology·Celeste E KiddHans A Hofmann
Mar 23, 2010·The American Naturalist·Tanya DettoPatricia R Y Backwell
Apr 16, 2010·Annals of the New York Academy of Sciences·Ralph Adolphs
Sep 21, 2010·Current Opinion in Neurobiology·James L Goodson, Richmond R Thompson
Jul 30, 2011·The Journal of Comparative Neurology·Lauren A O'Connell, Hans A Hofmann
Jan 31, 2012·Hormones and Behavior·Alexander G OphirSteven M Phelps
May 10, 2012·Frontiers in Neuroendocrinology·Lauren V Riters
Jun 2, 2012·Science·Lauren A O'Connell, Hans A Hofmann
Oct 9, 2012·Trends in Ecology & Evolution·Barbara Taborsky, Rui F Oliveira
Jan 10, 2014·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Ada C Felix-Ortiz, Kay M Tye
Jul 1, 2015·Hormones and Behavior·Kelsy S J ErvinElena Choleris
Jan 22, 2017·Hormones and Behavior·Chelsea A Weitekamp, Hans A Hofmann
Apr 28, 2017·Brain, Behavior and Evolution·Chelsea A WeitekampHans A Hofmann

❮ Previous
Next ❯

Citations

Sep 29, 2017·Integrative and Comparative Biology·Ben Dantzer, Dustin R Rubenstein
Mar 10, 2018·ACS Chemical Neuroscience·Karen P Maruska, Russell D Fernald

❮ Previous
Next ❯

Related Concepts

Related Feeds

Amygdala: Sensory Processes

Amygdalae, nuclei clusters located in the temporal lobe of the brain, play a role in memory, emotional responses, and decision-making. Here is the latest research on sensory processes in the amygdala.

Amygdala and Midbrain Dopamine

The midbrain dopamine system is widely studied for its involvement in emotional and motivational behavior. Some of these neurons receive information from the amygdala and project throughout the cortex. When the circuit and transmission of dopamine is disrupted symptoms may present. Here is the latest research on the amygdala and midbrain dopamine.