Neuromuscular diseases associated with chronic hepatitis C virus infection

Journal of Clinical Neuromuscular Disease
Joerg-Patrick Stübgen

Abstract

Hepatitis C virus (HCV) infection is a growing international health problem, and more than 170 million people are chronic carriers. Up to 50% of HCV-positive patients develop at least one extrahepatic manifestation during the course of disease. To varying degrees of certainty, there is evidence of an association between chronic HCV infection and a variety of neuromuscular diseases. The pathogenesis of most extrahepatic diseases remains unclear but possibly includes HCV lymphotropism and/or HCV-induced autoantibodies. The therapeutic approach to HCV-associated autoimmune disorders entails eradication of HCV with one of the recombinant interferon-alpha preparations with or without additional immunosuppressive drugs.

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Citations

Nov 3, 2012·International Journal of General Medicine·Marino ParoliDaniele Accapezzato
Apr 25, 2015·Current Problems in Diagnostic Radiology·Binit SurekaAnkur Arora

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