Neuromuscular Disorders and the Role of the Clinical Electrophysiologist

JACC. Clinical Electrophysiology
Haisam IsmailPeter Zimetbaum

Abstract

Cardiac involvement is common and may be the presenting or predominant manifestation in a variety of neuromuscular disorders, most notably the inherited muscle disorders, or muscular dystrophies. Cardiac manifestations of the neuromuscular disorders result from pathological involvement of the myocardium and the cardiac conduction system, with resulting cardiomyopathy or rhythm disturbances including supraventricular arrhythmias, life-threatening ventricular arrhythmias, and sudden cardiac death. Many of these neuromuscular disorders are rare and may be unrecognized by even experienced specialists in internal and cardiovascular medicine. Furthermore, the initial cardiac manifestations in these patients are often asymptomatic. The goal of this investigation is to review the scope of cardiac conduction defects and rhythm disturbances in these disorders and to propose some practical recommendations for arrhythmia monitoring and management of these patients.

References

Mar 1, 1978·Muscle & Nerve·W G BradleyP R Fawcett
Feb 1, 1990·Journal of the American College of Cardiology·W G StevensonT L Anderson
Mar 1, 1990·International Journal of Cardiology·G NigroR J Bain
Mar 1, 1989·European Heart Journal·P E PolakJ R Roelandt
May 7, 1987·The New England Journal of Medicine·B A Berko, M Swift
May 1, 1982·British Journal of Anaesthesia·W BuzelloA Schlickewei
May 1, 1993·Neuromuscular Disorders : NMD·A A ChenardY A Weiss
Dec 1, 1993·Journal of the American College of Cardiology·P MelaciniM L Mostacciuolo
Apr 15, 1993·The American Journal of Cardiology·L BadanoD Cannata
Mar 31, 1999·American Heart Journal·M YotsukuraK Ishikawa
Jul 17, 1999·Neuromuscular Disorders : NMD·E M HoogerwaardM de Visser
Jan 16, 2002·Journal of the Neurological Sciences·Giovanni MeolaL De Ambroggi
May 2, 2002·Cardiac Electrophysiology Review·Jose L Merino, Rafael Peinado
Feb 5, 2003·Neuromuscular Disorders : NMD·M A NolanH M Johnston
Mar 14, 2003·The American Journal of Cardiology·Candice K SilversidesDouglas W Biggar
Feb 5, 2004·American Heart Journal·Deepak BhaktaWilliam J Groh
Nov 20, 2004·Journal of Molecular Medicine : Official Organ of the Gesellschaft Deutscher Naturforscher Und Ärzte·Jop H van BerloYigal M Pinto
Feb 24, 2005·Neuromuscular Disorders : NMD·Werner KlinglerKarin Jurkat-Rott
Mar 24, 2005·Cardiology·Josef FinstererWolfgang Kopsa
May 24, 2005·Neuromuscular Disorders : NMD·Fabio GalettaGabriele Siciliano
Jan 13, 2006·The New England Journal of Medicine·Christophe MeuneDenis Duboc
Aug 28, 2007·American Heart Journal·Denis DubocHenri-Marc Bécane
Nov 14, 2007·Archives of Neurology·Douglas M SprouleDarryl C De Vivo
Jun 21, 2008·The New England Journal of Medicine·William J GrohRobert M Pascuzzi
Sep 25, 2008·European Journal of Pediatrics·L WelzingN Sreeram
Dec 1, 2009·Lancet Neurology·Katharine BushbyUNKNOWN DMD Care Considerations Working Group
Feb 24, 2010·Journal of Neurology, Neurosurgery, and Psychiatry·Chris Turner, David Hilton-Jones
Jul 16, 2010·Neuromuscular Disorders : NMD·M C E HermansC G Faber
Sep 22, 2010·Current Heart Failure Reports·Anitra Romfh, Elizabeth M McNally
Aug 10, 2011·Current Opinion in Neurology·Vincenzo NigroGiulio Piluso
Sep 16, 2011·International Journal of Cardiology·Helle PetriLars Køber
Sep 17, 2011·Muscle & Nerve·Luis Redondo-VergéGisèle Bonne
Jan 28, 2012·Journal of the American College of Cardiology·Ingrid A W van RijsingenYigal M Pinto
Mar 20, 2012·Journal of Electrocardiology·Josef FinstererHans Keller
Mar 29, 2012·JAMA : the Journal of the American Medical Association·Karim WahbiDenis Duboc

❮ Previous
Next ❯

Citations

Feb 23, 2020·Der Anaesthesist·J ProttengeierT Münster
Feb 19, 2020·Cardiology in Review·John N CatanzaroJohn N Makaryus
Jan 16, 2021·Breathe·Neeraj M ShahGeorgios Kaltsakas
Jul 24, 2020·Minerva medica·Alberto CiprianiDomenico Corrado

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiac Conduction System

The cardiac conduction system is a specialized tract of myocardial cells responsible for maintaining normal cardiac rhythm. Discover the latest research on the cardiac conduction system here.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.