Neuromuscular Fatigue and Metabolism during High-Intensity Intermittent Exercise

Medicine and Science in Sports and Exercise
Matteo FiorenzaJens Bangsbo

Abstract

To examine the degree of neuromuscular fatigue development along with changes in muscle metabolism during two work-matched high-intensity intermittent exercise protocols in trained individuals. In a randomized, counter-balanced, crossover design, 11 endurance-trained men performed high-intensity intermittent cycle exercise protocols matched for total work and including either multiple short-duration (18 × 5 s; SS) or long-duration (6 × 20 s; LS) sprints. Neuromuscular fatigue was determined by preexercise to postexercise changes in maximal voluntary contraction force, voluntary activation level and contractile properties of the quadriceps muscle. Metabolites and pH were measured in vastus lateralis muscle biopsies taken before and after the first and last sprint of each exercise protocol. Peak power output (11% ± 2% vs 16% ± 8%, P < 0.01), maximal voluntary contraction (10% ± 5% vs 25% ± 6%, P < 0.05), and peak twitch force (34% ± 5% vs 67% ± 5%, P < 0.01) declined to a lesser extent in SS than LS, whereas voluntary activation level decreased similarly in SS and LS (10% ± 2% vs 11% ± 4%). Muscle [phosphocreatine] before the last sprint was 1.5-fold lower in SS than LS (P < 0.001). Preexercise to postexercise intramuscular accum...Continue Reading

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Citations

May 29, 2019·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Matteo FiorenzaMorten Hostrup
Nov 22, 2019·International Journal of Sports Physiology and Performance·Theofanis TzatzakisIoannis G Fatouros
Aug 22, 2020·American Journal of Physiology. Heart and Circulatory Physiology·Matteo FiorenzaJens Bangsbo
Nov 10, 2020·Frontiers in Physiology·Leandro Henrique Albuquerque BrandãoMarzo Edir Da Silva-Grigoletto
Aug 23, 2020·Respiratory Physiology & Neurobiology·Ching-Feng ChengYu-Chi Kuo
Mar 19, 2021·Medicine and Science in Sports and Exercise·Teun VAN ErpRobert P Lamberts
Nov 18, 2021·Scandinavian Journal of Medicine & Science in Sports·Kleber J Da SilvaGuilherme A Ferreira

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