PMID: 9541207Apr 16, 1998Paper

Neuronal cells and neurotrophins in odontogenesis

European Journal of Oral Sciences
K Luukko

Abstract

There is evidence from lower animals that in addition to oral ectoderm and cranial neural crest, tooth formation depends on neuronal cells. To analyze the possible neural influence on mammalian tooth formation, peripheral nerve fibers and neuronal cells were localized in the area of the developing rat first molar tooth germ. Moreover, to study whether factors needed for neuronal development might be involved in the regulation of tooth formation and innervation, expression of NGF-related neurotrophic factors and their receptors were localized by in situ hybridization. The data suggest that although peripheral nerve fibers appear not to be required for odontogenesis, neuronal cells associated with the embryonic rat tooth may participate in the regulation of tooth formation. Localization of neurotrophins and their receptors suggests that besides their apparent roles in the regulation of tooth innervation, they may serve non-neuronal, organogenetic functions during tooth formation. Moreover, it is possible that neuronal characteristics of the dental mesenchymal cells and the presence of neuronal cells in the tooth germs may explain the specific ability of neural crest-derived, but no other mesenchymal, cells to contribute to mammal...Continue Reading

Citations

Jul 31, 2003·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Sigbjørn LøesPäivi Kettunen
Oct 12, 2005·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Keijo LuukkoPäivi Kettunen
Nov 25, 2003·European Journal of Oral Sciences·Vaska Vandevska-RadunovicInger Hals Kvinnsland
Mar 7, 2002·Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft·J C de VicenteJ A Vega
Mar 8, 2000·Mechanisms of Development·J Jernvall, I Thesleff
Jan 15, 2014·PloS One·Virginie Laugel-HaushalterAgnès Bloch-Zupan
May 24, 2005·Matrix Biology : Journal of the International Society for Matrix Biology·Jean-Christophe MaurinFrançoise Bleicher
Jun 26, 2001·American Journal of Physical Anthropology·E F HarrisB D Barcroft
Oct 24, 1998·Developmental Dynamics : an Official Publication of the American Association of Anatomists·K LuukkoI Thesleff
Aug 23, 2011·Archives of Oral Biology·A J SmithP R Cooper
Dec 11, 1999·Developmental Dynamics : an Official Publication of the American Association of Anatomists·O AmanoH C Slavkin
Jan 16, 2016·Cellular and Molecular Life Sciences : CMLS·John BiancoAnne des Rieux
Jun 11, 2019·Tissue Engineering. Part B, Reviews·Karim M Fawzy El-SayedChristof E Dörfer

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology
H I YooS H Kim
Developmental Dynamics : an Official Publication of the American Association of Anatomists
K LuukkoI Thesleff
© 2022 Meta ULC. All rights reserved