Neuronal transients

Proceedings. Biological Sciences
K J Friston

Abstract

A recent letter to Nature (Vaadia et al. Nature, Lond. 373, 515-518 (1995)) presented compelling results concerning neuronal interactions in monkey cortex. Vaadia et al. made two fundamental points: (i) it is possible that cortical function is mediated by dynamic modulation of coherent firing among neurons; and (ii) these time-dependent changes in correlations can emerge without modulation of firing rates. These observations have severe implications for models of neural coding and empirical approaches that are based on firing rates (e.g. neuroimaging). This communication presents a simpler explanation for the results presented in Vaadia et al., by noting they are consistent with the correlated expression of stereotyped neuronal transients following (or preceding) a salient event. This re-formulation is important because: (i) correlations measured in terms of transients are not time-dependent, allowing prevailing models of neural coding to be 'reinstated'; and (ii) it suggests a powerful analysis based on singular value decomposition of firing rates.

References

Jan 1, 1990·Biological cybernetics·P Földiák
Jan 1, 1990·Biological cybernetics·J Rubner, K Schulten
May 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·J A GallyG M Edelman
Aug 1, 1994·Current Opinion in Neurobiology·M N Shadlen, W T Newsome

❮ Previous
Next ❯

Citations

Jan 1, 1997·Human Brain Mapping·K J FristonR S Frackowiak
Jan 13, 2001·Neural Networks : the Official Journal of the International Neural Network Society·B HorwitzJ G Taylor
Feb 22, 2002·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Wilson A TruccoloSteven L Bressler
Mar 21, 2000·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·K J Friston
Sep 22, 1999·Neural Computation·C D Brody
Sep 22, 1999·Neural Computation·C D Brody
Apr 30, 2009·Journal of Cognitive Neuroscience·Marinella CappellettiCathy J Price
May 3, 2008·PLoS Computational Biology·Mikhail I RabinovichValentin S Afraimovich
Feb 1, 1997·NeuroImage·K J Friston
Apr 1, 1997·NeuroImage·K J Friston
Feb 25, 2009·NeuroImage·Marinella CappellettiVincent Walsh
Jan 4, 2003·Radiology·Kader Karli OguzDavid M Yousem
Oct 13, 2001·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·K J Friston
Nov 21, 2000·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·N D Schiff, F Plum
Jul 17, 1998·Neuroreport·J G TaylorH W Müller-Gärtner

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain Lower Grade Glioma

Low grade gliomas in the brain form from oligodendrocytes and astrocytes and are the slowest-growing glioma in adults. Discover the latest research on these brain tumors here.

Related Papers

Catheterization and Cardiovascular Diagnosis
J F KeaneD C Fyler
Journal of Neurology, Neurosurgery, and Psychiatry
S E NadeauK M Heilman
Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society
Hubertus AxerDiedrich Graf v Keyserlingk
© 2021 Meta ULC. All rights reserved