Neuronavigated Versus Non-navigated Repetitive Transcranial Magnetic Stimulation for Chronic Tinnitus: A Randomized Study

Trends in Hearing
Hanna SahlstenSatu K Jääskeläinen

Abstract

Repetitive transcranial magnetic stimulation (rTMS) has shown variable effect on tinnitus. A prospective, randomized 6-month follow-up study on parallel groups was conducted to compare the effects of neuronavigated rTMS to non-navigated rTMS in chronic tinnitus. Forty patients (20 men, 20 women), mean age of 52.9 years (standard deviation [ SD] = 11.7), with a mean tinnitus duration of 5.8 years ( SD = 3.2) and a mean tinnitus intensity of 62.2/100 ( SD = 12.8) on Visual Analog Scale (VAS 0-100) participated. Patients received 10 sessions of 1-Hz rTMS to the left temporal area overlying auditory cortex with or without neuronavigation. The main outcome measures were VAS scores for tinnitus intensity, annoyance, and distress, and Tinnitus Handicap Inventory (THI) immediately and at 1, 3, and 6 months after treatment. The mean tinnitus intensity (hierarchical linear mixed model: F3 = 7.34, p = .0006), annoyance ( F3 = 4.45, p = .0093), distress ( F3 = 5.04, p = .0051), and THI scores ( F4 = 17.30, p < .0001) decreased in both groups with non-significant differences between the groups, except for tinnitus intensity ( F3 = 2.96, p = .0451) favoring the non-navigated rTMS. Reduction in THI scores persisted for up to 6 months in both ...Continue Reading

References

Jan 1, 1988·Journal of Clinical Epidemiology·C D JenkinsR M Rose
Feb 1, 1996·Archives of Otolaryngology--head & Neck Surgery·C W NewmanJ B Spitzer
Apr 1, 1999·Journal of Clinical Psychology·R A SteerA T Beck
Apr 5, 2005·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Tobias KleinjungJuergen Strutz
Mar 4, 2006·ORL; Journal for Oto-rhino-laryngology and Its Related Specialties·Dirk De RidderAage R Moller
Oct 25, 2007·Progress in Brain Research·Aage R Møller
Dec 7, 2007·The Journal of Pain : Official Journal of the American Pain Society·Robert H DworkinStojan Zavisic
Dec 21, 2007·The Laryngoscope·Michael D SeidmanJinsheng Zhang
Jan 16, 2009·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Paul B FitzgeraldZafiris J Daskalakis
Apr 15, 2009·Hearing Research·Peyman AdjamianDeborah A Hall
Jul 21, 2009·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·R A MarcondesM A Marcolin
Oct 17, 2009·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Simone RossiUNKNOWN Safety of TMS Consensus Group
Mar 17, 2010·Neurophysiologie clinique = Clinical neurophysiology·B LangguthG Hajak
Jul 17, 2010·Brain Stimulation·Janna Marie HoogendamVincenzo Di Lazzaro
Jan 12, 2011·Neuron·Amber M LeaverJosef P Rauschecker
Feb 3, 2011·The Laryngoscope·Mark MennemeierJohn Dornhoffer
Mar 23, 2011·Archives of Otolaryngology--head & Neck Surgery·Jay F PiccirilloEdward L Spitznagel
Apr 16, 2011·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Florian ZemanMichael Landgrebe
May 17, 2011·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Berthold LangguthGöran Hajak
Jan 6, 2012·BMC Neuroscience·Harold BurtonJay F Piccirillo
Feb 22, 2012·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·S GroppaH R Siebner
Mar 3, 2012·Frontiers in Systems Neuroscience·Astrid LehnerBerthold Langguth
Jun 23, 2012·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Andre M WinelandJay Piccirillo
Aug 1, 2012·American Journal of Audiology·Ilya AdamchicPeter Alexander Tass
Aug 23, 2012·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·B LangguthT Kleinjung
Apr 20, 2013·Neuroscience and Biobehavioral Reviews·Dirk De RidderBerthold Langguth
Jul 6, 2013·Lancet·David BaguleyDeborah Hall
Jul 24, 2013·Neuroscience and Biobehavioral Reviews·Larry E RobertsJos J Eggermont
Jul 31, 2013·Hearing Research·Fatima T Husain, Sara A Schmidt
Aug 21, 2013·Lancet Neurology·Berthold LangguthDirk De Ridder
Jul 18, 2014·The Journal of Laryngology and Otology·P C L PintoA E Nardi
Jul 19, 2014·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Jean-Pascal LefaucheurLuis Garcia-Larrea
Oct 3, 2014·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·David E TunkelElizabeth J Whamond
May 15, 2015·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Robabeh SoleimaniTolou Hasandokht
Jun 19, 2015·International Journal of Audiology·Hanna SahlstenSatu K Jääskeläinen

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Nov 2, 2021·Voprosy kurortologii, fizioterapii, i lechebnoĭ fizicheskoĭ kultury·V B VoytenkovA A Komazov

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BETA
cochlear implants

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Software Mentioned

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SAS System
Visor2

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