Neuronavigation combined with electrophysiological monitoring for surgery of lesions in eloquent brain areas in 42 cases: a retrospective comparison of the neurological outcome and the quality of resection with a control group with similar lesions

Minimally Invasive Neurosurgery : MIN
T ReithmeierC B Lumenta

Abstract

The purpose of this study was to achieve a more radical resection of tumors in the area of the motor cortex via minimal craniotomy using a combination of neuronavigation and neurophysiological monitoring with direct electrical cortical stimulation and to compare retrospectively the clinical outcome and postoperative magnetic resonance imaging with a control group that was operated on in our service when the combination of these monitoring techniques was not available. A total of 42 patients with tumors in or near the central region underwent surgery with neuronavigation guidance and neurophysiological monitoring. The primary motor cortex was identified intraoperatively by the somatosensory evoked phase reversal method and direct cortical stimulation. The functional areas were transferred into the neuronavigation system. By stimulating the identified primary motor cortex and displaying the motor area in the operating microscope a permanent control of the motor function was possible during the whole operation. Using these techniques a more radical tumor resection - evaluated by postoperative MRI - was achieved in the study group (p = 0.04) and also a trend toward a better neurological outcome.

Citations

Sep 1, 2012·CNS Oncology·George M Ibrahim, Mark Bernstein
Jun 29, 2012·Acta neurochirurgica·Maria WostrackMichael Stoffel
Jul 20, 2005·Expert Review of Neurotherapeutics·Hugues Duffau
Oct 6, 2012·Clinical Neurology and Neurosurgery·Elke De Witte, Peter Mariën
Aug 21, 2012·Anesthesiology Clinics·Kirstin M Erickson, Daniel J Cole
Jul 4, 2012·Neurosurgery Clinics of North America·Matthew C GarrettLinda M Liau
Mar 26, 2011·Neurosurgery Clinics of North America·Laura RigoloSrinivasan Mukundan
Dec 18, 2015·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Iddo PaldorAndrew H Kaye
Dec 17, 2008·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Nobusada ShinouraKazuo Yagi
Oct 30, 2007·Neurologic Clinics·Ashok R AsthagiriMark E Shaffrey
Jun 2, 2012·Radiology Research and Practice·Chris SchulzUwe Max Mauer
Apr 14, 2010·Neurosurgery·Alessandro De BenedictisHugues Duffau
Jun 21, 2016·PLoS Computational Biology·Go AshidaDaniel J Tollin
Jan 16, 2007·Arquivos de neuro-psiquiatria·Stênio Abrantes SarmentoHelder Tedeschi
Dec 24, 2005·Acta neurochirurgica·T PichtO Suess
Nov 22, 2017·Nature Reviews. Clinical Oncology·Nader Sanai, Mitchel S Berger
Nov 20, 2012·Current Opinion in Neurology·Nader Sanai
May 26, 2018·Journal of Neurosurgery·Malte OttenhausenTheodore H Schwartz
Aug 26, 2021·Journal of Neurological Surgery. Part A, Central European Neurosurgery·Henry ColleChris van der Linden

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