Neurons in the posterior insular cortex are responsive to gustatory stimulation of the pharyngolarynx, baroreceptor and chemoreceptor stimulation, and tail pinch in rats

Brain Research
Takamitsu HanamoriH Kannan

Abstract

Extracellular unit responses to gustatory stimulation of the pharyngolaryngeal region, baroreceptor and chemoreceptor stimulation, and tail pinch were recorded from the insular cortex of anesthetized and paralyzed rats. Of the 32 neurons identified, 28 responded to at least one of the nine stimuli used in the present study. Of the 32 neurons, 11 showed an excitatory response to tail pinch, 13 showed an inhibitory response, and the remaining eight had no response. Of the 32 neurons, eight responded to baroreceptor stimulation by an intravenous (i.v.) injection of methoxamine hydrochloride (Mex), four were excitatory and four were inhibitory. Thirteen neurons were excited and six neurons were inhibited by an arterial chemoreceptor stimulation by an i.v. injection of sodium cyanide (NaCN). Twenty-two neurons were responsive to at least one of the gustatory stimuli (deionized water, 1.0 M NaCl, 30 mM HCl, 30 mM quinine HCl, and 1.0 M sucrose); five to 11 excitatory neurons and three to seven inhibitory neurons for each stimulus. A large number of the neurons (25/32) received converging inputs from more than one stimulus among the nine stimuli used in the present study. Most neurons (23/32) received converging inputs from different ...Continue Reading

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Citations

Jan 8, 2004·Brain Research Bulletin·Terence V Sewards
Nov 13, 2015·Brain Research·María M HurtadoAmadeo Puerto
May 8, 2015·Human Brain Mapping·Jason A AveryW Kyle Simmons
Jan 11, 2017·Human Brain Mapping·Jason A AveryW Kyle Simmons
Oct 21, 2006·Nature Reviews. Neuroscience·Sidney A SimonMiguel A L Nicolelis
Feb 29, 2020·Experimental Biology and Medicine·Stephanie M StaszkoMax L Fletcher
Sep 3, 2002·Journal of Neurophysiology·Karleyton C EvansDouglas R Corfield
Dec 31, 2002·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Cinthia V PastuskovasRobert L Thunhorst
Jan 2, 2021·Proceedings of the National Academy of Sciences of the United States of America·Jason A AveryAlex Martin
Jan 20, 2021·Neuroscience·Mohammed Gamal-EltrabilyMiguel Condés-Lara
Jun 14, 2019·Neuroscience and Biobehavioral Reviews·Morgan M Rogers-Carter, John P Christianson

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