Neuropathic osteoarthropathy with and without superimposed osteomyelitis in patients with a diabetic foot

Skeletal Radiology
Antonio LeoneCesare Colosimo

Abstract

Soft tissue and bone infection involving the foot is one of the most common long-term complications of diabetes mellitus, implying a serious impairment in quality of life for patients in the advanced stages of the disease. Neuropathic osteoarthropathy often coexists and differentiating between these two entities is commonly challenging, but crucial, as the management may differ substantially. The importance of correct diagnosis cannot be understated and effective management requires a multidisciplinary approach owing to the complicated nature of therapy in such patients. A missed diagnosis has a high likelihood of major morbidity for the patient, including limb amputation, and over-diagnosis results in a great socioeconomic challenge for healthcare systems, the over-utilization of healthcare resources, and the unwise use of antibiotics. Diagnosis is largely based on clinical signs supplemented by various imaging modalities such as radiography, MR imaging, and hybrid imaging techniques such as F-18 fluorodeoxyglucose-positron emission tomography. In the interests of the management of diabetic foot complications, this review article is aimed on the one hand at providing radiologists with important clinical knowledge, and on the o...Continue Reading

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Citations

Oct 28, 2019·La Radiologia medica·Antonio LeoneCesare Colosimo
Dec 5, 2019·International Journal of Molecular Sciences·Camilo A Ruiz-BedoyaSanjay K Jain
Nov 16, 2021·The International Journal of Lower Extremity Wounds·Gabriela Verónica CarroMiguel Ticona Ortiz

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