Neuropathic pain in leprosy: symptom profile characterization and comparison with neuropathic pain of other etiologies

Pain Reports
Irina RaicherDaniel Ciampi de Andrade

Abstract

Previous studies reported a high prevalence of neuropathic pain in leprosy, being especially present in "pharmacologically cured" patients. The presence of neuropathic pain in leprosy poses a supplementary burden in patient's quality of life, daily activities, and mood. The aim of this study was to assess whether neuropathic pain in leprosy has similar symptom profile as neuropathic pain of other etiologies and to retrospectively assess the efficacy of neuropathic pain medications regularly prescribed to leprosy. Leprosy and nonleprosy patients had their neuropathic pain characterized by the neuropathic pain symptom inventory (NPSI, ranges from 0 to 100, with 100 being the maximal neuropathic pain intensity) in a first visit. In a second visit, leprosy patients who had significant pain and received pharmacological treatment in the first evaluation were reassessed (NPSI) and had their pain profile and treatment response further characterized, including information on drugs prescribed for neuropathic pain and their respective pain relief. The pain characteristics based on NPSI did not significantly differ between leprosy and nonleprosy neuropathic pain patients in visit 1 after correction for multiple analyses, and cluster analys...Continue Reading

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Citations

Feb 11, 2020·Frontiers in Immunology·Débora Bartzen Moraes AngstMárcia Rodrigues Jardim
Aug 25, 2021·BMC Infectious Diseases·Louise Mara GieselMarcia Rodrigues Jardim
Sep 24, 2021·PLoS Neglected Tropical Diseases·Liliane Marques de Pinho TiagoIsabela Maria Bernardes Goulart
Nov 21, 2021·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Gigi J Ebenezer, David M Scollard

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