PMID: 9447621Feb 3, 1998Paper

Neuropathology of pediatric brain tumors

Seminars in Pediatric Neurology
A T Yachnis

Abstract

Pediatric central nervous system neoplasms include a spectrum of both glial and nonglial tumors that differ significantly in location and biological behavior from those of adults. Brain tumors in infants and children most often arise from central neuroepithelial tissue, whereas a significant number of adult tumors arise from central nervous system coverings (e.g., meningioma), adjacent tissue (e.g., pituitary adenoma), or metastases. Most adult brain tumors are supratentorial malignant gliomas, whereas the most common malignant pediatric brain tumor is the cerebellar primitive neuroectodermal tumor (medulloblastoma). This article reviews neuropathological characteristics of the more common pediatric brain tumors. Entities, such as the brainstem glioma, and less common neoplasms like the desmoplastic infantile ganglioglioma and the central nervous system atypical teratoid/rhabdoid tumor are reviewed because they occur almost exclusively in children. Known cytogenetic and molecular characteristics of childhood brain tumors are also reviewed.

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Citations

May 8, 1999·Seminars in Roentgenology·L A Loevner
Nov 26, 1999·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·R H GoldbrunnerJ C Tonn
Jan 5, 2008·Skull Base : Official Journal of North American Skull Base Society ... [et Al.]·Sam Safavi-AbbasiMadjid Samii
Apr 28, 2005·Expert Review of Neurotherapeutics·Katherine E Warren, Roger J Packer
May 17, 2002·Veterinary Pathology·Q WuB S Carson
Jul 3, 2008·Applied Immunohistochemistry & Molecular Morphology : AIMM·Wendy A Chamberlain, Richard A Prayson
Apr 19, 2000·Arquivos de neuro-psiquiatria·J S Reis FilhoL F Torres
Jul 19, 2013·Journal of the American Animal Hospital Association·Isidro MateoAlberto Muñoz

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