PMID: 6167672Jan 1, 1981Paper

Neuropeptides in striato-nigral pathways

Journal of Neural Transmission
A C CuelloJ V Priestley

Abstract

The existence of a neuronal pathway containing Leu-enkephalin and connecting the neostriatum with the globus pallidus has been confirmed combining immunohistochemistry with microinjections of neurotoxic agents (kainic acid, colchicine) and discrete knife lesions. The presence of substance P in nerve terminals of the substantia nigra was demonstrated by the application of a monoclonal antibody against this peptide. Electron microscopic studies revealed immunoreactive sites for substance P in nerve terminals establishing symmetric and asymmetric synapses, mainly over dendritic profiles. The possible peptide-containing neuronal pathways in the nigro-striatal system are discussed.

References

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Citations

Dec 1, 1984·Italian Journal of Neurological Sciences·A Albanese, M C Altavista
Mar 1, 1986·Neuroscience·J K MaiA C Cuello
Jan 1, 1990·Neuroscience·J M Giménez-Amaya, A M Graybiel
Jun 1, 1986·The Japanese Journal of Psychiatry and Neurology·H Sato
Jan 9, 2013·The Journal of Comparative Neurology·Kalynda Kari GonzalesYoland Smith
Jun 7, 1986·Journal of Theoretical Biology·R Barker
Sep 14, 1986·Biochemical and Biophysical Research Communications·W H BoydD Jichici
Mar 31, 2000·Experimental Neurology·L MenalledM F Chesselet
Nov 15, 1993·The Journal of Comparative Neurology·J RodrigoJ M Polak
Dec 1, 1985·European Journal of Clinical Microbiology·R ToshniwalC A Kallick
Apr 1, 1988·Zeitschrift Für Lebensmittel-Untersuchung Und -Forschung·C Fernández Pereira

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