In the kissing bug Rhodnius prolixus, events such as diuresis, antidiuresis, development and reproduction are triggered by blood feeding. Hence, these events can be accurately timed, facilitating physiological experiments. This, combined with its relatively big size, makes R. prolixus an excellent model in insect neuroendocrinological studies. The importance of R. prolixus as a Chagas' disease vector as much as an insect model has motivated the sequencing of its genome in recent years, facilitating genetic and molecular studies. Most crucial physiological processes are regulated by the neuroendocrine system, composed of neuropeptides and their receptors. The identification and characterization of neuropeptides and their receptors could be the first step to find targets for new insecticides. The sequences of 41 neuropeptide precursor genes and the receptors for most of them were identified in the R. prolixus genome. Functional information about many of these molecules was obtained, whereas many neuroendocrine systems are still unstudied in this model species. This review addresses the knowledge available to date regarding the structure, distribution, expression and physiological effects of neuropeptides in R. prolixus, and point...Continue Reading
Changes in hormone activity of single neurosecretory cell bodies during a physiological secretion cycle
Secretory activities of plasmatocytes and oenocytoids during the moulting cycle in an insect (Rhodnius)
A family of neuropeptides that inhibit juvenile hormone biosynthesis in the cricket, Gryllus bimaculatus.
Antioxidant role of Rhodnius prolixus heme-binding protein. Protection against heme-induced lipid peroxidation.
Effects of two neuronal antidiuretic molecules, neuroparsin and 5-hydroxytryptamine, on cytosolic free calcium monitored with indo-1 in epithelial and muscular cells of the African locust rectum
Isolation, sequence determination, physical and physiological characterization of the neuroparsins and ovary maturing parsins of Schistocerca gregaria
The distribution of a kinin-like peptide and its co-localization with a CRF-like peptide in the blood-feeding bug, Rhodnius prolixus
Neuropeptides in the nervous system of Drosophila and other insects: multiple roles as neuromodulators and neurohormones
Evidence for CRF-like and kinin-like peptides as neurohormones in the blood-feeding bug, Rhodnius prolixus
The distribution and effects of Dippu-allatostatin-like peptides in the blood-feeding bug, Rhodnius prolixus
The distribution and activity of tachykinin-related peptides in the blood-feeding bug, Rhodnius prolixus
Serotonin: a coordinator of feeding-related physiological events in the blood-gorging bug, Rhodnius prolixus
Distribution, activity and evidence for the release of an anti-diuretic peptide in the kissing bug Rhodnius prolixus
Electrochemical gradients for Na+, K+, Cl- and H+ across the apical membrane in Malpighian (renal) tubule cells of Rhodnius prolixus
Evidence for a role of orcokinin-related peptides in the circadian clock controlling locomotor activity of the cockroach Leucophaea maderae
RNA interference of the salivary gland nitrophorin 2 in the triatomine bug Rhodnius prolixus (Hemiptera: Reduviidae) by dsRNA ingestion or injection
Molecular characterization and cell-specific expression of an ion transport peptide in the tobacco hornworm, Manduca sexta
Neuroanatomical relations of prothoracicotropic hormone neurons with the circadian timekeeping system in the brain of larval and adult Rhodnius prolixus (Hemiptera)
Characterization of neuropeptide F-like immunoreactivity in the blood-feeding hemipteran, Rhodnius prolixus
Peptidomics: the integrated approach of MS, hyphenated techniques and bioinformatics for neuropeptide analysis
Isolation, cloning, and expression mapping of a gene encoding an antidiuretic hormone and other CAPA-related peptides in the disease vector, Rhodnius prolixus
Biological activity of diuretic factors on the anterior midgut of the blood-feeding bug, Rhodnius prolixus
Toward the development of novel pest management agents based upon insect kinin neuropeptide analogues
Peptidergic clock neurons in Drosophila: ion transport peptide and short neuropeptide F in subsets of dorsal and ventral lateral neurons
Functions of ion transport peptide and ion transport peptide-like in the red flour beetle Tribolium castaneum
In search for a common denominator for the diverse functions of arthropod corazonin: a role in the physiology of stress?
The antidiuretic neurohormone RhoprCAPA-2 downregulates fluid transport across the anterior midgut in the blood-feeding insect Rhodnius prolixus
Physiological activity of neuropeptide f on the hindgut of the blood-feeding hemipteran, Rhodnius prolixus
Bombyx prothoracicostatic peptides activate the sex peptide receptor to regulate ecdysteroid biosynthesis
Isolation, expression analysis, and functional characterization of the first antidiuretic hormone receptor in insects
Isolation, cloning and expression of the Crustacean Cardioactive Peptide gene in the Chagas' disease vector, Rhodnius prolixus
Genomics and peptidomics of neuropeptides and protein hormones present in the parasitic wasp Nasonia vitripennis
Biostable multi-Aib analogs of tachykinin-related peptides demonstrate potent oral aphicidal activity in the pea aphid Acyrthosiphon pisum (Hemiptera: Aphidae)
Identification of the elusive peptidergic diuretic hormone in the blood-feeding bug Rhodnius prolixus: a CRF-related peptide
Crustacean cardioactive peptide in the Chagas' disease vector, Rhodnius prolixus: presence, distribution and physiological effects
The receptor guanylate cyclase Gyc76C and a peptide ligand, NPLP1-VQQ, modulate the innate immune IMD pathway in response to salt stress
Cloning of the cDNA, localization, and physiological effects of FGLamide-related allatostatins in the blood-gorging bug, Rhodnius prolixus
Biostable and PEG polymer-conjugated insect pyrokinin analogs demonstrate antifeedant activity and induce high mortality in the pea aphid Acyrthosiphon pisum (Hemiptera: Aphidae)
Natriuresis and diuretic hormone synergism in R. prolixus upper Malpighian tubules is inhibited by the anti-diuretic hormone, RhoprCAPA-α2
The distribution and physiological effects of the myoinhibiting peptides in the kissing bug, rhodnius prolixus
Identification, spatial expression analysis and functional characterization of a pyrokinin-1 receptor in the Chagas' disease vector, Rhodnius prolixus
Insulin-like and testis ecdysiotropin neuropeptides are regulated by the circadian timing system in the brain during larval-adult development in the insect Rhodnius prolixus (Hemiptera)
The female reproductive system of the kissing bug, Rhodnius prolixus: arrangements of muscles, distribution and myoactivity of two endogenous FMRFamide-like peptides
The molecular characterization of the kinin transcript and the physiological effects of kinins in the blood-gorging insect, Rhodnius prolixus
Identification and expression of the CCAP receptor in the Chagas' disease vector, Rhodnius prolixus, and its involvement in cardiac control
Transcriptome analysis of neuropeptides and G-protein coupled receptors (GPCRs) for neuropeptides in the brown planthopper Nilaparvata lugens
Structure-activity relationships of FMRF-NH2 peptides demonstrate A role for the conserved C terminus and unique N-terminal extension in modulating cardiac contractility
Evidence for a conserved CCAP-signaling pathway controlling ecdysis in a hemimetabolous insect, Rhodnius prolixus
Isolation and functional characterization of calcitonin-like diuretic hormone receptors in Rhodnius prolixus
Effects of chitin synthase double-stranded RNA on molting and oogenesis in the Chagas disease vector Rhodnius prolixus
The gap gene Krüppel of Rhodnius prolixus is required for segmentation and for repression of the homeotic gene sex comb-reduced
Synergistic induction of the clock protein PERIOD by insulin-like peptide and prothoracicotropic hormone in Rhodnius prolixus (Hemiptera): implications for convergence of hormone signaling pathways
Identification of uncoupling protein 4 from the blood-sucking insect Rhodnius prolixus and its possible role on protection against oxidative stress
Reprint of "The distribution and physiological effects of three evolutionarily and sequence-related neuropeptides in Rhodnius prolixus: Adipokinetic hormone, corazonin and adipokinetic hormone/corazonin-related peptide"
Daily variation of the response to heat in Rhodnius prolixus: the roles of light and temperature as synchronisers
Functional characterization and expression analysis of the myoinhibiting peptide receptor in the Chagas disease vector, Rhodnius prolixus
Identification and characterization of receptors for ion transport peptide (ITP) and ITP-like (ITPL) in the silkworm Bombyx mori.
Identification, characterization and expression of a receptor for the unusual myosuppressin in the blood-feeding bug, Rhodnius prolixus
Myoinhibitors controlling oviduct contraction within the female blood-gorging insect, Rhodnius prolixus
Identification and functional characterization of FGLamide-related allatostatin receptor in Rhodnius prolixus
The effect of convection on infrared detection by antennal warm cells in the bloodsucking bug Rhodnius prolixus
Ovary ecdysteroidogenic hormone requires a receptor tyrosine kinase to activate egg formation in the mosquito Aedes aegypti
Identification of G protein coupled receptors for opsines and neurohormones in Rhodnius prolixus. Genomic and transcriptomic analysis
The Nutrient-Responsive Hormone CCHamide-2 Controls Growth by Regulating Insulin-like Peptides in the Brain of Drosophila melanogaster
Identification and characterization of the adipokinetic hormone/corazonin-related peptide signaling system in Rhodnius prolixus
Adipokinetic hormone receptor gene identification and its role in triacylglycerol metabolism in the blood-sucking insect Rhodnius prolixus
Conserved molecular switch interactions in modeled cardioactive RF-NH2 peptide receptors: Ligand binding and activation
Orcokinins contribute to the regulation of vitellogenin transcription in the cockroach Blattella germanica
Genome of Rhodnius prolixus, an insect vector of Chagas disease, reveals unique adaptations to hematophagy and parasite infection
Identification of the first insulin-like peptide in the disease vector Rhodnius prolixus: Involvement in metabolic homeostasis of lipids and carbohydrates
Correction for Mesquita et al., Genome of Rhodnius prolixus, an insect vector of Chagas disease, reveals unique adaptations to hematophagy and parasite infection
Identification and characterization of capa and pyrokinin genes in the brown marmorated stink bug, Halyomorpha halys (Hemiptera): Gene structure, immunocytochemistry, and differential expression
Plodia interpunctella (Lepidoptera: Pyralidae): Intoxication with essential oils isolated from Lippia turbinata (Griseb.) and analysis of neuropeptides and neuropeptide receptors, putative targets for pest control
Genome-wide identification of neuropeptides and their receptor genes in Bemisia tabaci and their transcript accumulation change in response to temperature stresses.
Characterization and Expression Profiling of Neuropeptides and G-Protein-Coupled Receptors (GPCRs) for Neuropeptides in the Asian Citrus Psyllid, Diaphorina citri (Hemiptera: Psyllidae)
Transcriptomics supports local sensory regulation in the antenna of the kissing-bug Rhodnius prolixus
Identification and Characterization of GPCRs for Pyrokinin and CAPA Peptides in the Brown Marmorated Stink Bug, Halyomorpha halys (Hemiptera: Pentatomidae)
Genomics, transcriptomics, and peptidomics of Spodoptera frugiperda (Lepidoptera, Noctuidae) neuropeptides.
Insulin receptor deficiency reduces lipid synthesis and reproductive function in the insect Rhodnius prolixus.
The neuropeptide RhoprCCHamide2 inhibits serotonin-stimulated transcellular Na+ transport across the anterior midgut of the vector of Chagas disease, Rhodnius prolixus.
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