PMID: 8582760Oct 1, 1995Paper

Neuropharmacological effects of ivermectin in mice

Indian Journal of Physiology and Pharmacology
R S Kanwar, C Varshneya

Abstract

Neuropharmacological effects (Spontaneous locomotor activity, forced locomotor activity and anticonvulsant activity) of invermectin were studied at 400, 800 and 1600 micrograms/kg (administered, subcutaneously). Spontaneous locomotor activity was reduced at all the dose levels but forced locomotor activity was slightly reduced at 800 and 1600 micrograms/kg. The drug did not exhibit any anticonvulsant potential at any of the dose levels studied.

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