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Neuropharmacological mechanisms of nerve agent-induced seizure and neuropathology

Neuroscience and Biobehavioral Reviews

Sep 1, 1997

John H McDonough, T M Shih

PMID: 9353792

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Abstract

This paper proposes a three phase "model" of the neuropharmacological processes responsible for the seizures and neuropathology produced by nerve agent intoxication. Initiation and early expression of the seizures are cholinergic phenomenon; anticholinergics readily terminate seizures a...read more

Mentioned in this Paper

Anticholinergic [EPC]
Amino Acid [EPC]
N-Methyl-D-Aspartate Receptors
Cholinesterase Inhibitors, Reversible
Neurotransmitters
Benzodiazepines Assay
Transcription Initiation
Calcium [EPC]
Anticholinergic Agents
N-Methylaspartate
58
Paper Details
References
  • References128
  • Citations340
12345...
  • References128
  • Citations340
12345...

Neuropharmacological mechanisms of nerve agent-induced seizure and neuropathology

Neuroscience and Biobehavioral Reviews

Sep 1, 1997

John H McDonough, T M Shih

PMID: 9353792

DOI:

Abstract

This paper proposes a three phase "model" of the neuropharmacological processes responsible for the seizures and neuropathology produced by nerve agent intoxication. Initiation and early expression of the seizures are cholinergic phenomenon; anticholinergics readily terminate seizures a...read more

Mentioned in this Paper

Anticholinergic [EPC]
Amino Acid [EPC]
N-Methyl-D-Aspartate Receptors
Cholinesterase Inhibitors, Reversible
Neurotransmitters
58

Related Papers

Paper Details
References
  • References128
  • Citations340
12345...
  • References128
  • Citations340
12345...

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