PMID: 7027896Apr 1, 1981Paper

Neuropharmacological regulation of pituitary hormones. Role of acetylcholine, gamma-aminobutyric acid, histamine and endorphins (author's transl)

Annales d'endocrinologie
R Martin-du Pan, F Gomez

Abstract

The secretion of pituitary hormones is controlled by hypothalamic hormones which are synthetized by neurosecreting cells whose activity is modulated by different neurotransmitters as dopamine and serotonin. Centrally acting drugs interfere with the activity of these neurotransmitters. Thus they may influence the secretion of pituitary hormones. Acetylcholine, gamma-aminobutyric acid, histamine and endorphins seem also to influence the pituitary secretion. The endocrine effects of drugs (opiates, antiparkinson, antiepileptic, and antihistaminic agents) acting on these neurotransmitters is reviewed.

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