PMID: 6168341Jul 1, 1981Paper

Neurophysiological and biochemical properties of the goldfish optic tectum maintained in vitro

Brain Research Bulletin
T J TeylerV E Shashoua

Abstract

The physiology and biochemistry of the in vitro goldfish optic tectum are examined. Following surgical removal of the intact optic tectum by severing its connectives, the tectal explant is maintained in a brain slice chamber in a specified medium for up to 24 hours. Electrophysiological studies show that the in vitro tectum displays the same response properties to optic nerve stimulation as does an in vivo tectum. Concurrent biochemical studies that RNA and protein synthesis is actively maintained for at least 17 hrs in vitro. Thus both biochemical and electrophysiological measurements indicate that the integrity of the tectal explant can be maintained in vitro making it a suitable model system for investigations of a variety of neurobiological questions.

References

Aug 1, 1979·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·J T Schmidt
Nov 1, 1978·The Journal of Comparative Neurology·J Meek, N A Schellart
Jan 15, 1979·Experimental Brain Research·H VanegasJ A Freeman
Nov 1, 1976·Brain Research Bulletin·J D O'Benar
Jan 1, 1976·Cold Spring Harbor Symposia on Quantitative Biology·M G Yoon
May 17, 1973·Brain Research·H VanegasE Essayag-Millán
Mar 1, 1974·The Journal of Comparative Neurology·H VanegasJ Amat
Oct 1, 1981·Journal of Neuroscience Methods·C A Curcio, K R Sloan
Jul 1, 1980·Brain Research Bulletin·T J Teyler
Jan 1, 1963·Experimental Neurology·D G ATTARDI, R W SPERRY

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Citations

Jul 23, 2013·Journal of Neuroscience Research·Brad J Kolls, Ronald L Meyer
Jun 11, 1986·Brain Research·D Lewis, T J Teyler
Jan 1, 1983·Biological cybernetics·S Hampson, D Kibler

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