Neurophysiological correlates of unconditioned and conditioned feeding behavior in the pond snail Lymnaea stagnalis

Journal of Neurophysiology
K StarasPaul R Benjamin

Abstract

We used a behavioral appetitive learning paradigm followed by electrophysiological analysis to investigate the neuronal expression of appetitive conditioning in Lymnaea. We first established the levels of unconditioned and conditioned feeding responses in intact animals. We then demonstrated that neuronal correlates of both unconditioned responses to touch and food and a conditioned response to touch could be found in semi-intact preparations of the same animals that had been subjected to behavioral tests and conditioning trials. In the conditioning experiments, the experimental animals received 15 trials in which touch to the lips, the conditioned stimulus (CS), was paired with sucrose, the unconditioned food stimulus (US). Control animals received 15 presentations of either CS or US, or both, applied in a random manner. After training, a strong conditioned response to touch was established in the experimental but not in the control groups. For subsequent electrophysiological analysis of posttraining neuronal responses to the touch CS, semi-intact preparations were set up from the same animals that had been behaviorally conditioned or subjected to control procedures. Intracellular recordings, made from previously identified mo...Continue Reading

References

Jan 1, 1986·Annual Review of Neuroscience·T J Carew, C L Sahley
Sep 1, 1989·Behavioral and Neural Biology·G Kemenes, P R Benjamin
Apr 1, 1987·Physiological Reviews·J H Byrne
Sep 1, 1987·Behavioral and Neural Biology·M D Tuersley, C R McCrohan
Dec 1, 1985·Journal of Neurophysiology·C J Elliott, P R Benjamin
Jan 1, 1984·Journal of Neurobiology·J AlexanderG J Audesirk
Jun 25, 1984·Brain Research·A Gelperin, N Culligan
Dec 1, 1982·Behavioral and Neural Biology·T E AudesirkC M Moyer
Jan 1, 1995·Neurobiology of Learning and Memory·I Izquierdo, J H Medina

❮ Previous
Next ❯

Citations

Apr 14, 2004·Journal of Neuroscience Research·John T BirminghamDavid L Tauck
Jun 17, 2011·Archives of Insect Biochemistry and Physiology·Samuel S LiuAdalberto A Pérez de León
Aug 4, 2015·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·S KojimaE Ito
Mar 14, 2013·Nature Communications·Vincenzo MarraIldikó Kemenes
Jun 4, 2016·Nature Communications·Michael CrossleyGyörgy Kemenes
May 12, 2000·Neuroscience Letters·S KobayashiE Ito
Jan 28, 2003·Current Biology : CB·Kevin StarasGyörgy Kemenes
Nov 16, 2006·Analytical Chemistry·Bhavik Anil PatelDanny O'Hare

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.