Neurophysiological effects of mistletoe (Viscum album L.) on isolated rat intestines

Phytotherapy Research : PTR
M RadenkovicS Veljkovic

Abstract

Mistletoe (Viscum album L.) is well known as a medicine from ancient times and the earliest notes. Today it is used as a remedy. The aim of this research was to examine the effects of mistletoe extracts and their components on some neurophysiological parameters in rat intestines. The tonus and contractile responses of isolated intestinal segments (duodenum, ileum and distal colon) were analysed. The experiment was carried out in three groups. In the first group (control group) different concentrations of acetylcholine were added into the organ bath (10-50 nmol/L). In the second group, mistletoe extracts were added into the organ bath with increasing concentrations and in the third group, atropine, a non-selective muscarinic receptor antagonist, was added into the organ bath (concentration 10(-7) mol/L) and after atropine plant extracts were administered. The results obtained suggest that extracts from different parts of mistletoe have neurophysiological effects and change intestinal contractions. The results also suggest that the effects of mistletoe extracts on intestinal contractility act via cholinergic pathways, activating muscarinic receptors in the intestines. However, in order to establish the subtype of receptors, furth...Continue Reading

References

Apr 1, 1986·Planta medica·H WagnerZ Kalogjera
Aug 6, 2000·Zeitschrift Für Naturforschung. C, a Journal of Biosciences·E WollenweberK Haas
Aug 18, 2001·Planta medica·P CosD Vanden Berghe

❮ Previous
Next ❯

Citations

Jan 28, 2009·Clinical and Experimental Hypertension : CHE·Mirjana RadenkovicLjiljana Gvozdenovic
Apr 6, 2016·Frontiers in Physiology·Layanne C da Cunha AraujoBagnólia A da Silva
Mar 28, 2012·Journal of Ethnopharmacology·Gaurav GuptaFiroz Anwar
Jul 27, 2010·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Dubravka BigovicSlavoljub Zivanovic
Oct 2, 2015·Bioscience Reports·Layanne Cabral da Cunha AraujoBagnólia Araújo da Silva
Jul 21, 2020·Oxidative Medicine and Cellular Longevity·Anderson Fellyp Avelino DinizBagnólia Araújo da Silva
Dec 1, 2018·Oxidative Medicine and Cellular Longevity·Iara L L de SouzaBagnólia A da Silva
Aug 10, 2021·Oxidative Medicine and Cellular Longevity·Anderson Fellyp Avelino DinizBagnólia Araújo da Silva

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.