PMID: 10515665Oct 9, 1999Paper

Neurophysiological support of consciousness during waking and sleep

Progress in Neurobiology
Claude Gottesmann

Abstract

The aim of this review was to try to establish the current neurophysiological knowledge capable of explaining the differences of mental functioning during the different stages of sleep and waking. The analysis focused on the cortical state. Waking is characterized by electrophysiological activities (low voltage and gamma range EEG field patterns, unitary activities) and cerebral blood flow reflecting an activated state. On the contrary, neurochemical influences are marked by inhibitory afferent processes since dopamine, noradrenaline, serotonin and histamine tend, for the most part, to inhibit cortical neurons by diffuse release at the level of varicosities. During slow wave sleep, all these brain stem influences sustaining the cortical state decrease and transiently disappear just prior to onset of REM sleep. During REM sleep, pontine and mesopontine ascending activating influences invade the cortex in their turn while neurochemical inhibitory influences disappear with the exception of dopaminergic ones. We hypothesize that the activating influences acting on the cortex allow the latter to function, just as petrol makes an engine run, but that the diffuse inhibitory influences somehow regulate cortex functioning. Therefore, it...Continue Reading

References

Feb 1, 1977·Electroencephalography and Clinical Neurophysiology·F BelardettiM Mancia
Mar 1, 1979·Electroencephalography and Clinical Neurophysiology·A RougeulO Debray
Aug 1, 1976·European Journal of Pharmacology·S Kafi, J M Gaillard
Aug 15, 1975·Life Sciences·J C Schwartz
Nov 1, 1979·Brain Research Bulletin·C ArnaudC Gottesmann
Jan 13, 1978·Brain Research·P Levitt, R Y Moore
Feb 18, 1977·Brain Research·H L Haas, P Wolf
Jul 30, 1976·Brain Research·A Beaudet, L Descarries
Aug 1, 1976·European Journal of Pharmacology·B S Sastry, J W Phillis
Dec 26, 1975·Brain Research·L DescarriesK C Watkins
Jan 23, 1976·Brain Research·D J McGinty, R M Harper
Dec 1, 1992·Synapse·J Day, H C Fibiger
Jun 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·V N Murthy, E E Fetz
Dec 3, 1991·European Journal of Pharmacology·J M MontiS Olivera
Jul 1, 1991·Electroencephalography and Clinical Neurophysiology·P G Ray, W J Jackson
Jan 1, 1991·Neuroscience·R R Llinás, D Paré
Dec 15, 1991·Proceedings of the National Academy of Sciences of the United States of America·U RibaryR Llinás
Feb 22, 1991·Science·T Sawaguchi, P S Goldman-Rakic
May 1, 1991·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·P L MadsenG Wildschiødtz
May 15, 1991·Proceedings of the National Academy of Sciences of the United States of America·M SteriadeG Oakson

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Citations

Mar 22, 2005·Psychopharmacology·Hsiao Ying ChenCheryl C H Yang
Apr 1, 2006·Experimental Brain Research·Hans C DringenbergJennifer Murdoch
Sep 11, 2007·Experimental Brain Research·Inga GriskovaSidse M Arnfred
Apr 11, 2013·Applied Psychophysiology and Biofeedback·Paul Lehrer, David Eddie
Oct 19, 2010·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Nan-Tsing ChiuYen Kuang Yang
Jan 20, 2004·Neuroscience Letters·Akira TeraoThomas S Kilduff
Jul 28, 2001·Progress in Neurobiology·C Gottesmann
Apr 18, 2002·Neuroscience Letters·Roumen Kirov, Slavianka Moyanova
Feb 1, 2003·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Tomoka TakeuchiAnthony V Ferrelli
Sep 11, 2002·Journal of Sleep Research·Troels W KjaerPeter L Madsen
Jul 12, 2002·Psychiatry and Clinical Neurosciences·Claude Gottesmann
Jul 7, 2011·International Journal of General Medicine·Serge Brand, Roumen Kirov
Feb 7, 2006·Médecine sciences : M/S·Claude Gottesmann
Aug 3, 2010·Neurophysiologie clinique = Clinical neurophysiology·F Guénolé, A Nicolas
Nov 19, 2003·The European Journal of Neuroscience·Hans C Dringenberg, Min-Ching Kuo
Jul 2, 2008·Annals of the New York Academy of Sciences·Nicholas D Schiff
Nov 8, 2001·Consciousness and Cognition·T TakeuchiK Belicki
May 24, 2012·The Behavioral and Brain Sciences·Roumen KirovJuliana Yordanova
Feb 12, 2020·Scientific Reports·Sumire MatsumotoKaspar E Vogt
Sep 30, 2005·Anesthesiology·Satoshi HagihiraTakashi Mashimo

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