Neurophysiology and SPECT cerebral blood flow patterns in dementia

Electroencephalography and Clinical Neurophysiology
E P SloanJ M MacLennan

Abstract

A series of elderly patients with dementia of Alzheimer type (AD), multi-infarct dementia (MID) and functional (non-organic) psychiatric illness (major depressive disorder) were selected by DSM III-R criteria and had the following investigations: a battery of cognitive tests, EEG with power and coherence spectral analyses of T4-T6, T3-T5, P4-O2, P3-O1 channels, visual evoked potential (flash and pattern reversal) and P300 recordings as well as single photon emission tomography (SPECT) using 99mTc HMPAO. Three subsets of patients were chosen on clinical and SPECT criteria. These were as follows: patients with a clinical diagnosis of AD and a SPECT rCBF pattern showing bilateral temporo-parietal perfusion deficits (AD type), patients with a clinical diagnosis of MID and a SPECT rCBF pattern showing single focal perfusion deficits or multiple areas of low perfusion in the cerebral cortex suggestive of ischaemic change (MID type SPECT picture) and functionally ill patients with normal rCBF (controls). The AD type group differed from the MID rCBF group in having significantly less alpha and more delta 2 (2- < 4 Hz) power. The latter had significantly lower alpha power than the controls. The 2 dementia groups with abnormal rCBF patte...Continue Reading

References

Dec 1, 1978·Brain : a Journal of Neurology·D S GoodinA Starr
Jul 1, 1992·Electroencephalography and Clinical Neurophysiology·E P Sloan, G W Fenton
May 1, 1990·Electroencephalography and Clinical Neurophysiology·J PolichF E Bloom
Jul 1, 1990·Electroencephalography and Clinical Neurophysiology·D S Goodin
Jul 1, 1990·Electroencephalography and Clinical Neurophysiology·A PfefferbaumH C Kraemer
Jul 1, 1990·Neurobiology of Aging·J T MarshD Kuhl
Feb 1, 1989·Journal of Neurology, Neurosurgery, and Psychiatry·A BurnsR Levy
Jul 5, 1986·British Medical Journal·A OrwinE B Rolfe
May 1, 1988·The British Journal of Psychiatry : the Journal of Mental Science·C E Wright, P L Furlong
Nov 1, 1985·The British Journal of Psychiatry : the Journal of Mental Science·G F HardingA Orwin
May 1, 1984·Electroencephalography and Clinical Neurophysiology·C E WrightA Orwin
Nov 1, 1994·Journal of Neurology, Neurosurgery, and Psychiatry·C D Binnie, P F Prior
Sep 1, 1955·Journal of Abnormal Psychology·J E DOPPELT, W L WALLACE

❮ Previous
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Citations

Jan 1, 1997·European Archives of Psychiatry and Clinical Neuroscience·T J MüllerW K Strik
Jun 1, 1993·Electroencephalography and Clinical Neurophysiology·E P Sloan, G W Fenton
Jun 19, 2004·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Jaeseung Jeong
Sep 22, 1998·Electroencephalography and Clinical Neurophysiology·T LocatelliG Comi
Apr 21, 1999·Brain Research. Brain Research Reviews·W Klimesch
Aug 11, 2004·Behavioral Neuroscience·Claudio BabiloniPaolo Maria Rossini
Dec 22, 1999·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·L Leocani, G Comi
Jan 1, 1996·Acta Neurologica Scandinavica. Supplementum·E Ryding
Feb 15, 2005·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Kerry L CoburnYashica S Marshall
Mar 18, 2006·Journal of Integrative Neuroscience·David M AlexanderEvian Gordon
Jan 5, 2002·Acta Clinica Belgica·P Cras
Jul 1, 1997·Clinical EEG (electroencephalography)·N C Moore
Aug 12, 2006·Journal of Child Neurology·Agnes S Chan, Winnie W M Leung
Mar 23, 2018·Journal of Alzheimer's Disease : JAD·Harald HampelUNKNOWN Alzheimer Precision Medicine Initiative (APMI)
Jun 13, 2000·Arquivos de neuro-psiquiatria·R AnghinahA C Melo
Apr 17, 2021·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Claudio BabiloniBahar Guntekin

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