Neuropsychodynamic Approach to Depression: Integrating Resting State Dysfunctions of the Brain and Disturbed Self-Related Processes

Frontiers in Human Neuroscience
Heinz Boeker, Rainer Kraehenmann

Abstract

A mechanism-based approach was developed focusing on the psychodynamic, psychological and neuronal mechanisms in healthy and depressed persons. In this integrative concept of depression, the self is a core dimension in depression. It is attributed to negative emotions (e.g., failure, guilt). The increased inward focus in depression is connected with a decreased environmental focus. The development of neuropsychodynamic hypotheses of the altered self-reference is based on the investigation of the emotional-cognitive interaction in depressed patients. It may be hypothesized that the increased negative self-attributions-as typical characteristics of an increased self-focus in depression-may result from altered neuronal activity in subcortical-cortical midline structures in the brain, especially from hyperactivity in the cortical-subcortical midline regions and hypoactivity in the lateral regions. The increased resting state activity in depression is especially associated with an increased resting state activity in the default mode network (DMN) and a dysbalance between DMN and executive network (EN) activity. Possible therapeutic consequences of the neuropsychodynamic approach to depression involve the necessary emotional attuneme...Continue Reading

References

Feb 1, 1976·Psychiatry·J C Coyne
Jan 1, 1991·Journal of the American Psychoanalytic Association·C Brenner
Mar 1, 1994·Journal of Personality·E L DeciD R Leone
Jan 1, 1997·Journal of Psychopharmacology·D L Masterman, J L Cummings
Jan 23, 1998·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·K J FristonR Turner
Jan 27, 1998·The Journal of Nervous and Mental Disease·S ParadisoR G Robinson
Mar 14, 1998·Proceedings of the National Academy of Sciences of the United States of America·K J Friston
Mar 17, 1998·NeuroImage·K J FristonR Turner
Dec 30, 1999·Scientific American·A R Damasio
Jan 5, 2000·Psychological Medicine·F C MurphyE S Paykel
Mar 17, 2000·Brain Research. Brain Research Reviews·G Tononi, G M Edelman
Aug 30, 2000·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·L PelosiV K Sharma
Nov 7, 2000·Biological Psychiatry·W C Drevets
Feb 24, 2001·Proceedings of the National Academy of Sciences of the United States of America·M E RaichleG L Shulman
Mar 22, 2001·Proceedings of the National Academy of Sciences of the United States of America·D A GusnardM E Raichle
Apr 5, 2001·Brain Research Bulletin·K J Friston, C J Price
May 16, 2001·Psychological Medicine·F C MurphyB J Sahakian
Jul 13, 2001·Nature·M E Raichle
Oct 5, 2001·Nature Reviews. Neuroscience·D A GusnardM E Raichle
Jan 22, 2002·Biological Psychiatry·Richard J Davidson
Apr 12, 2002·Journal of Psychosomatic Research·Mary-Frances O'ConnorAlfred W Kaszniak
Jul 2, 2002·Archives of General Psychiatry·Rebecca ElliottRaymond J Dolan
Aug 15, 2002·Proceedings of the National Academy of Sciences of the United States of America·L PessoaL G Ungerleider
Nov 5, 2002·Trends in Cognitive Sciences·Cathy J. Price, Karl J. Friston
Nov 27, 2002·The American Journal of Psychiatry·Helen Mayberg
Dec 3, 2002·Neuropsychologia·Bruno WickerJean Decety
Dec 18, 2002·Journal of Neural Transmission·G Northoff
Dec 25, 2002·Cognition·Vinod Goel, Raymond J Dolan
Dec 31, 2002·The American Journal of Psychiatry·Richard J DavidsonNed H Kalin
Dec 31, 2002·Proceedings of the National Academy of Sciences of the United States of America·Michael D GreiciusVinod Menon
Apr 15, 2003·Trends in Cognitive Sciences·Karl J. Friston, Cathy J. Price
Aug 30, 2003·Biological Psychiatry·Mary L PhillipsRichard Lane
Sep 2, 2003·NeuroImage·K J FristonW Penny
Sep 10, 2003·The Behavioral and Brain Sciences·Georg Northoff
Oct 11, 2003·Biological Psychiatry·Veena KumariTonmoy Sharma
Oct 24, 2003·Brain Research. Brain Research Reviews·Bruno WickerPierre Fonlupt
Oct 28, 2003·Zeitschrift für Psychosomatische Medizin und Psychotherapie·Henning Schauenburg, John Clarkin
Nov 5, 2003·The American Journal of Psychiatry·Harald GündelRichard D Lane

❮ Previous
Next ❯

Methods Mentioned

BETA
Cognitive Behavioral Therapy

Related Concepts

Related Feeds

Attention Disorders

Attention is involved in all cognitive activities, and attention disorders are reported in patients with various neurological diseases. Here are the latest discoveries pertaining to attention disorders.

© 2022 Meta ULC. All rights reserved