Neuropsychological assessment in children with absence epilepsy

Neurology
P PavoneE Parano

Abstract

To define cognitive deficits in children with absence epilepsy. Cognitive deficits have often been reported in children with epilepsy, but have rarely been characterized in patients with a specific epileptic syndrome. Detailed neuropsychological testing was carried out on 16 right-handed children with absence epilepsy with similar clinical and EEG findings, and the findings were compared to 16 well-matched right-handed children without absence epilepsy. The authors found lower scores of measures of general cognitive functioning and visuospatial skills in patients with absence epilepsy, as compared to controls. Memory disturbances were also detected in absence epilepsy patients, with selective involvement of nonverbal memory and delayed recall. In contrast, verbal memory and language skills were relatively preserved. Patients whose seizures began at an earlier age seemed to have more severe cognitive deficits. Language skills tend to be relatively well preserved in children with generalized epilepsy, with more dysfunction seen in global terms rather than specific lateralizing deficits. Patients with absence epilepsy seem to show a similar neurocognitive profile that may be a reflection of the underlying epilepsy syndrome.

Citations

Oct 27, 2007·Neuropsychology Review·William S MacAllister, Sarah G Schaffer
Jun 26, 2004·Current Neurology and Neuroscience Reports·Samuel Wiebe
May 18, 2004·Epilepsy & Behavior : E&B·Fugen SonmezBaki Arpaci
Feb 11, 2003·Epilepsy Research·Melinda A NolanAnn M E Bye
Nov 19, 2008·Nature Clinical Practice. Neurology·Gregory N Barnes, Juliann M Paolicchi
Aug 7, 2010·Nature Reviews. Neurology·Pasquale Striano, Carlo Minetti
Mar 5, 2010·The New England Journal of Medicine·Tracy A GlauserUNKNOWN Childhood Absence Epilepsy Study Group
Jul 2, 2010·The Neurologist·Deivasumathy Muthugovindan, Adam L Hartman
Feb 23, 2002·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Frank M C Besag
May 9, 2007·Epilepsia·Jose L Perez VelazquezO Carter Snead
Jun 19, 2008·Epilepsia·Rochelle CaplanW Donald Shields
Jul 25, 2009·Epilepsia·Rochelle CaplanW Donald Shields
Nov 7, 2012·Epilepsia·Claudia L KernanRochelle Caplan
Sep 22, 2007·Annual Review of Medicine·B A Leeman, A J Cole
Jul 11, 2013·Epilepsy Currents·Jeffrey R Tenney, Tracy A Glauser
Mar 29, 2014·Current Treatment Options in Neurology·Jeffrey R Tenney, Sejal V Jain
Apr 22, 2014·Experimental Neurology·Ivanka Savic
Jan 9, 2016·Neuroscience·José Eduardo Marques-CarneiroJean-Christophe Cassel
Sep 23, 2014·Epilepsy & Behavior : E&B·Linda M GonzalezAmanda G Wood
Dec 3, 2014·Seizure : the Journal of the British Epilepsy Association·Leanne Menlove, Colin Reilly
Dec 1, 2011·Neurologia i neurochirurgia polska·Dorota TalarskaMichał Michalak
Feb 18, 2014·Pediatric Neurology·Sara MatricardiPaolo Curatolo
Jun 20, 2014·Neurobiology of Disease·Ivanka Savic, Jerome Engel
May 24, 2012·Neuroscience and Biobehavioral Reviews·Radwa A B BadawyAnthony S Harvey
Dec 6, 2011·Clinical Therapeutics·Shannon N SaldañaTracy A Glauser
Feb 7, 2015·Pediatric Annals·Jun T ParkAdham Jammoul
Dec 17, 2015·Journal of the Neurological Sciences·A VerrottiG Coppola
Oct 16, 2015·Neurobiology of Disease·Robert J HeuermannDane M Chetkovich
Mar 1, 2011·Acta Paediatrica·Alberto VerrottiPaolo Curatolo
Jun 23, 2009·Journal of Neuropsychology·Kati RantanenKai Eriksson
Nov 22, 2012·Epilepsia·Tracy A GlauserUNKNOWN Childhood Absence Epilepsy Study Team
Oct 24, 2003·Seminars in Pediatric Neurology·Warren A MarksMarsha Gabriel
May 19, 2007·Pediatric Neurology·Heidi A BenderCharles M Zaroff
Sep 25, 2012·Behavioral and Brain Functions : BBF·Ayşe KarsonNurbay Ateş
Aug 27, 2005·Neuroscience and Biobehavioral Reviews·Caroline HommetMaryse Lassonde
Sep 12, 2014·Epilepsia·Ettore BeghiCarol S Camfield

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Absence Epilepsy

Absence epilepsy is a common seizure disorder in children which can produce chronic psychosocial sequelae. Discover the latest research on absence epilepsies here.