PMID: 11902321Mar 21, 2002Paper

Neuropsychological changes after surgical treatment for temporal lobe epilepsy

Epilepsia
M WachiY Sohma

Abstract

The effect of unilateral temporal lobectomy on seizure frequency is well recognized, but little is known about the neuropsychological changes that occur after surgical treatment. We assessed neuropsychological status in 26 patients with an average age of 35 years before and after unilateral temporal lobectomy for medically intractable TLE. Neuropsychological examination to assess cognitive function, memory, attention, visuospatial analysis, language, and emotional functions was performed preoperatively and at 1 month and 1 year after the surgery. At both 1 month and 1 year after the surgery, the patients had improved scores, compared with the preoperative scores, on the Wechsler Adult Intelligence Scale-Revised (WAIS-R: verbal IQ, performance IQ, and full-scale IQ), Wechsler Memory Scale-Revised (WMS-R: verbal, general, and delayed paired associates memory), and Raven Colored Progressive Matrices. In the Minnesota Multiphasic Personality Inventory (MMPI), significant decreases were observed at 1 year after the surgery in the scores for infrequency, hypochondriasis, psychasthenia, and schizophrenia. Patients in whom the seizures had been relieved postoperatively also had improved scores on the WAIS-R, WMS-R, and Raven Colored Pr...Continue Reading

Citations

Feb 6, 2014·Neurosurgical Review·Dario J Englot, Edward F Chang
Mar 1, 2012·Journal of Neuro-oncology·Martin KleinPhilip C De Witt Hamer
Mar 18, 2004·Journal of Neurology, Neurosurgery, and Psychiatry·R LuerdingA Ebner
Jan 30, 2004·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Roger E KelleyRegina Brunson
Jul 22, 2014·Seizure : the Journal of the British Epilepsy Association·Virginie VoltzenlogelLiliann Manning
Jul 30, 2015·Epilepsy Research·Virginie VoltzenlogelLiliann Manning
May 29, 2015·Epilepsy & Behavior : E&B·Edward F ChangSumeet Vadera
Sep 23, 2008·Seizure : the Journal of the British Epilepsy Association·Liliana G GrammaldoAngelo Picardi
Jan 12, 2005·Seizure : the Journal of the British Epilepsy Association·Peter MattssonEva Kumlien
May 5, 2012·Epilepsy & Behavior : E&B·Elisabeth Engman, Kristina Malmgren
Jan 3, 2015·Revue neurologique·B MathonS Clemenceau

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