Neuropsychological consequences of antihypertensive medication use

Experimental Aging Research
M F MuldoonJ Richard Jennings

Abstract

A growing proportion of the general population is being prescribed antihypertensive medications for the long-term treatment of essential hypertension. Untreated hypertensive individuals exhibit some neuropsychological performance decrements, and numerous researchers have sought to determine whether drug therapy for hypertension worsens, improves, or leaves unaltered objectively measured cognitive skills. These issues may be especially important in the elderly, among whom both high blood pressure and compromised cognitive function are common. In this review, we collate the findings of more than 50 clinical studies according to class of antihypertensive medication studied and domains of neuropsychological performance assessed. Special attention is given to investigations of elderly subjects, and a critical summary is provided.

References

Jan 31, 1979·Psychopharmacology·A A LandauerF W Prott
Dec 18, 1978·European Journal of Clinical Pharmacology·E HeidbrederA Heidland
Aug 1, 1979·Experimental Aging Research·C A PentzJ Dineen
Mar 1, 1992·American Journal of Hypertension·J A Beto, V K Bansal
Apr 1, 1992·Journal of Psychosomatic Research·J E Dimsdale, R P Newton
Jun 1, 1991·Journal of Hypertension·M F MuldoonS R Waldstein
Dec 1, 1990·Journal of Clinical Pharmacology·B JohnsonJ Johnson
Apr 1, 1989·Journal of Cardiovascular Pharmacology·J ConantM LeWinter
Jan 1, 1988·British Journal of Clinical Pharmacology·G Frcka, M Lader
Jan 1, 1985·European Journal of Clinical Pharmacology·T A BettsD Mortiboy
Jan 1, 1985·European Journal of Clinical Pharmacology·D Harms
Jul 1, 1988·American Heart Journal·S StreufertM Piasecki
Jan 1, 1985·Psychopharmacology·D Olajide, M Lader
Jun 1, 1986·British Journal of Clinical Pharmacology·I LichterM A Wyke
Jan 1, 1988·Neuroscience and Biobehavioral Reviews·J S Turkkan
Jan 1, 1986·Psychopharmacology·D J MaddenD C McKee
Nov 1, 1988·Journal of the American Geriatrics Society·B J GurlandS Edlavitch
Apr 1, 1988·Archives of Internal Medicine·F M GengoP R Kinkel
Apr 1, 1988·Clinical Pharmacology and Therapeutics·J A BlumenthalJ Simon
Jun 26, 1986·The New England Journal of Medicine·S H CroogG H Williams
Jun 1, 1986·Acta Neurologica Scandinavica·A MazzucchiM Parma
Jan 1, 1985·European Journal of Clinical Pharmacology·P van RooyA J Cilliers
Jan 1, 1986·Journal of the American College of Cardiology·Y YuiC Kawai
Jul 1, 1985·Journal of Gerontology·T A Salthouse, W Lichty
Jan 1, 1985·European Journal of Clinical Pharmacology·P Van GelderW H Tsui
Jan 1, 1984·British Journal of Clinical Pharmacology·G HawksworthA Parsons
Mar 1, 1984·Journal of Pediatric Orthopedics·A KaufmanS Duban
Oct 1, 1983·Archives of General Psychiatry·S SolomonR S Blum
Jan 1, 1984·British Journal of Clinical Pharmacology·S A Salem, D G McDevitt
Sep 1, 1981·Drugs·F E Husserl, F H Messerli

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Citations

Jun 14, 2012·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Juan C KupfermanSteven G Pavlakis
Sep 28, 2007·Journal of General Internal Medicine·Joseph V AgostiniJohn Concato
Sep 12, 2000·Current Hypertension Reports·M L Seux, F Forette
Dec 4, 2003·Health Psychology : Official Journal of the Division of Health Psychology, American Psychological Association·Shari R Waldstein, Merrill F Elias
Dec 15, 2005·Neuropsychology·Christopher B BradyJ Michael Gaziano
Oct 1, 1995·Experimental Aging Research·S R Waldstein
Jul 20, 2010·Psychosomatic Medicine·J Richard JenningsCarolyn C Meltzer
Jun 28, 2011·Clinical Journal of the American Society of Nephrology : CJASN·Marc B LandeJoseph T Flynn
Jun 11, 2005·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·Shari R WaldsteinLeslie I Katzel
Jun 6, 2013·Journal of the American Society of Hypertension : JASH·Michael L AloscoJohn Gunstad
Jun 8, 2012·The Journal of Clinical Hypertension·Marc B LandeHeather R Adams
Sep 6, 2005·Primary Care·Michael MaddensAyham Ashkar
Mar 25, 2000·Journal of the American Geriatrics Society·M A RobbinsM F Elias
May 5, 2009·NeuroImage·J Richard Jennings, Ydwine Zanstra
Aug 24, 1999·Current Opinion in Nephrology and Hypertension·J M Starr
Aug 13, 2002·Journal of Hypertension·Matthew F MuldoonStephen B Manuck

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