Neuropsychological deficits are associated with smoking cessation treatment failure in patients with schizophrenia

Schizophrenia Research
Sara L DolanTony P George

Abstract

Schizophrenics have deficits in neuropsychological performance, some of which are modified by cigarette smoking. These patients also have high rates of smoking and resistance to smoking cessation interventions. We examined whether the presence of neuropsychological deficits prior to smoking cessation treatment was associated with smoking cessation treatment failure in schizophrenic as compared to non-psychiatric control smokers. Neuropsychological assessments were performed prior to treatment with pharmacological agents during the course of placebo-controlled trials in schizophrenic and non-psychiatric control smokers, and included the Wisconsin Card Sorting Test (WCST), a Visuospatial Working Memory (VSWM) task, the Stroop Color Word Test (SCWT) and the Continuous Performance Test (CPT). In schizophrenics (n=32), subjects who had greater deficits in VSWM and WCST performance were significantly less likely to quit smoking, but this association was not observed in controls (n=40). Differences between quitters and non-quitters were not likely related to atypical antipsychotic treatment or differences in depressive symptoms. No associations between baseline performance on CPT or SCWT and quit status were found in either group. The...Continue Reading

References

Sep 1, 1991·British Journal of Addiction·T F HeathertonK O Fagerström
Jan 1, 1988·Schizophrenia Bulletin·T E Goldberg, D R Weinberger
Jun 1, 1995·Journal of Neurology, Neurosurgery, and Psychiatry·L Cipolotti, E K Warrington
Apr 15, 1995·Biological Psychiatry·J McEvoyJ Rose
Sep 1, 1995·Schizophrenia Research·M Davidson, R S Keefe
Jan 1, 1996·Schizophrenia Bulletin·R Morice, A Delahunty
Aug 1, 1996·Biological Psychiatry·H T NagamotoR Freedman
Sep 1, 1996·Psychological Medicine·J P MialetD Yurgelun-Todd
Nov 1, 1996·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·E D LevinJ McEvoy
Dec 15, 1996·Schizophrenia Research·H H HeppM Spitzer
Jan 21, 1997·Proceedings of the National Academy of Sciences of the United States of America·R FreedmanW Byerley
Jan 1, 1997·Journal of Psychopharmacology·M B Knable, D R Weinberger
May 30, 1998·Cerebral Cortex·E V SullivanA Pfefferbaum
Jun 5, 1998·Schizophrenia Bulletin·L E AdlerR Freedman
Jan 23, 1999·Biological Psychiatry·J I FriedmanK L Davis
Jul 8, 1999·Biological Psychiatry·J P McEvoyW H Wilson
Nov 26, 1999·Proceedings of the National Academy of Sciences of the United States of America·H Y MeltzerR Kessler
Apr 28, 2000·The American Journal of Psychiatry·G A LightD L Braff
Feb 7, 2001·The American Journal of Psychiatry·P D Harvey, R S Keefe
Jun 8, 2001·Proceedings of the National Academy of Sciences of the United States of America·M F EganD R Weinberger
Nov 6, 2001·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·A E EvinsD C Goff
Dec 26, 2001·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Tony P GeorgeBruce E Wexler
Jan 15, 2002·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Ric M ProcyshynSean Flynn
Apr 16, 2002·Journal of Consulting and Clinical Psychology·Ellen S BurgessIvan W Miller
Jun 14, 2002·Biological Psychiatry·Michael F GreenJim Mintz
Jun 25, 2002·Biological Psychiatry·Tony P GeorgeThomas R Kosten
Jul 26, 2002·Journal of the American Academy of Dermatology·David S RubensteinThomas N Darling
Sep 13, 2002·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Robert C SmithAngelica Kloos
Jan 28, 2003·Biological Psychiatry·Tony P GeorgeStephanie S O'Malley
Mar 1, 1993·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·M D FranzenW D MacInnes

❮ Previous
Next ❯

Citations

Jun 27, 2007·The Journal of Clinical Psychiatry·Risa B Gershon GrandArthur L Brody
Nov 26, 2008·The Journal of Clinical Psychiatry·Melissa A CulhaneA Eden Evins
Dec 9, 2010·International Journal of Environmental Research and Public Health·Timothy C DurazzoSara Jo Nixon
Apr 20, 2007·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Ruth S BarrA Eden Evins
Dec 15, 2005·Journal of Abnormal Psychology·Junghee Lee, Sohee Park
Mar 10, 2016·Asian Journal of Psychiatry·Muhammad Chanchal AzadTanvir Chowdhury Turin
Sep 8, 2009·Drug and Alcohol Dependence·Freda PattersonCaryn Lerman
Jun 10, 2015·Neuroscience and Biobehavioral Reviews·F Scott HallJared W Young
Feb 10, 2007·Psychiatry Research·Amanda BakerKristen Moeller-Saxone
Oct 11, 2008·Journal of Psychiatric and Mental Health Nursing·C R MartinJ Atkinson
Nov 29, 2008·Behavioral Sciences & the Law·Sara L DolanPeter E Nathan
Dec 2, 2011·Annals of the New York Academy of Sciences·Victoria C WingTony P George
Jul 16, 2013·Schizophrenia Research·Victoria C WingTony P George
Sep 14, 2016·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Beatriz López-LuengoMiguel García-Cobo
Oct 10, 2007·The Australian and New Zealand Journal of Psychiatry·Carissa M CoulstonChristopher C Tennant
Oct 27, 2017·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Freda PattersonDavid G Edwards
Feb 4, 2010·Plastic and Reconstructive Surgery·Tommaso Agostini, Vittorugo Agostini
Feb 11, 2020·JMIR Mental Health·Mary F BrunetteHaiyi Xie
Aug 13, 2020·Journal of Clinical and Experimental Neuropsychology·Orkun AydınPınar Ünal-Aydın
Jun 17, 2009·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·Brian HitsmanTony P George
Jun 30, 2018·The Mental Health Clinician·Avery E Shawen, Shannon J Drayton

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