PMID: 6981734Oct 1, 1982Paper

Neuropsychological dysfunction following elective cardiac operation. I. Early assessment

The Journal of Thoracic and Cardiovascular Surgery
J A SavageauM D Klein

Abstract

Two neuropsychological tests were administered to 227 men and women, ages 25 to 69 years, before and after coronary bypass and cardiac valve operations to provide current information regarding the incidence of postoperative decrements in neuropsychological dysfunction and the factors associated with them. Biographical, psychological, and medical-surgical data were studied together with changes in scores on the Trail Making Tests and the Visual Reproduction (VR) Test of the Wechsler Memory Scale (WMS). Postoperative decrements greater than one standard deviation were observed in each of the four scores derived from these testings for 11% to 17% of the patients. Yet 70% of all patients remained within one standard deviation of original performance on all four scores. Among the preoperative correlates of significantly reduced test performance were age greater than 60 years, end-diastolic pressure greater than 30 mm Hg, moderate to severely enlarged heart size on preoperative x-ray film, and use of propranolol or chlordiazepoxide hydrochloride. Significant perioperative correlates included measure of duration of operation (such as total time of operation greater than 7 hours, time on the pump greater than 2 hours, and aortic cross-...Continue Reading

Citations

Dec 29, 2011·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Monisha A Kumar
Jan 1, 1990·Social Science & Medicine·C D JenkinsC A Stroup-Benham
Dec 1, 1989·Journal of the American College of Cardiology·R R SchallM Jessup
Feb 5, 2004·The Annals of Thoracic Surgery·P Michael HoKarl E Hammermeister
Aug 8, 2001·Journal of the Neurological Sciences·A Di CarloD Inzitari
Apr 12, 1986·Lancet·P L SmithM J Harrison
Mar 1, 1997·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·G VingerhoetsC Jannes
Apr 1, 1997·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·A WelzB Reichart
Dec 15, 2005·Heart, Lung & Circulation·Mark A SaderDavid S Celermajer
Mar 1, 1994·Archives of Environmental Health·D BellingerH L Needleman
Sep 1, 1998·Cognitive Neuropsychology·M J RiddochT Heafield
Nov 22, 2008·Applied Neuropsychology·Kriscinda A WhitneyStephanie Callaway
Sep 2, 2011·Neurocase·Peter MariënJo Verhoeven
Feb 1, 2013·Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition·Lina PezzutiArturo Orsini
Jul 16, 2005·The Clinical Neuropsychologist·Tanis J FermanNeill R Graff-Radford
Oct 1, 1995·Addiction·A W DeckelV Hesselbrock
Apr 1, 1992·Alcoholism, Clinical and Experimental Research·R Gillen, V Hesselbrock
Oct 1, 1996·Alcoholism, Clinical and Experimental Research·A W Deckel, V Hesselbrock
Mar 1, 1990·Acta Psychiatrica Scandinavica·A RossiM Casacchia
Oct 2, 2012·Annual Review of Psychology·Adele Diamond
Apr 1, 1991·Journal of Neurosurgery·B P HermannG Somes
May 8, 2013·Journal of Cardiothoracic and Vascular Anesthesia·Suzan Uysal, David L Reich
Apr 9, 2008·Progress in Brain Research·Nicole CazaGilbert Blaise
May 1, 1984·Stroke; a Journal of Cerebral Circulation·S D BrinkmanL A Jacobs
Jul 1, 1990·Brain Injury : [BI]·J M BurkeJ M Kerrigan
Oct 1, 1994·Brain Injury : [BI]·M C Stratton, R J Gregory
Apr 1, 1989·Psychological Reports·H R SearightJ L Gibbons
Jan 8, 2014·Journal of Clinical and Experimental Neuropsychology·Jérémy BesnardDidier Le Gall
Jan 1, 1986·International Journal of Psychiatry in Medicine·A V DeatonJ Skenazy

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