PMID: 9529829Apr 8, 1998Paper

Neuropsychological impairments following hantavirus pulmonary syndrome

Journal of the International Neuropsychological Society : JINS
R O HopkinsE D Bigler

Abstract

Recently an outbreak of acute respiratory infection associated with the hantavirus occurred in the southwestern United States. Hantavirus pulmonary syndrome (HPS) is a life threatening illness that carries with it a high mortality rate. Patients with HPS experience prolonged periods of hypoxemia requiring mechanical ventilation and treatment in intensive care units. We have recently seen 2 survivors of HPS. A neuropsychological test battery was administered immediately following their acute hospitalization and at 1 year postrecovery from HPS. Both patients exhibited cognitive impairments immediately following HPS as well as persistent cognitive impairments at 1 year. The cognitive impairments seen in these two HPS survivors are similar to those seen in other patients who have experienced brain anoxia, including memory impairments. It is also possible that hantavirus may directly cause brain injury with concomitant cognitive impairments. Additional research needs to be carried out in order to determine the extent and severity of the cognitive impairments in survivors of HPS.

Citations

Jun 1, 2001·Current Infectious Disease Reports·Marilyn Fabbri, Melanie J. Maslow
Apr 2, 2005·Journal of the International Neuropsychological Society : JINS·Ramona O HopkinsJames F Orme
Apr 10, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·C J Peters, Ali S Khan
Nov 19, 2004·Intensive Care Medicine·Sharon M GordonRamona O Hopkins
May 5, 2012·Critical Reviews in Microbiology·Maria SargianouGeorge Panos

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