Abstract
Vascular cognitive impairment (VCI) is characterized by cognitive compromise predominantly of executive dysfunction. To assess cognitive functions in VCI, focusing on executive functions, to observe functional losses in relation to activities of daily living (ADLs) and to detect early symptoms prior to the onset of dementia. We evaluated healthy subjects matched for gender, education and age to patients with diagnosis of subcortical vascular disease who had a stroke classified into three groups: 1) vascular lesions and no impairment; 2) vascular cognitive impairment with no dementia (VCIND); 3) vascular dementia (VaD). The performance on neuropsychological tests differed among groups, worsening with increased impairment level. The probable VaD group demonstrated impaired performance in memory, processing speed and verbal production, while the VCIND group showed attention deficits. Impairment in executive functions and difficulties in ADLs allow us to differentiate levels of impairment in groups of subcortical vascular disease.
References
Dec 1, 1991·Annals of Neurology·W A RoccaT J Heeren
Feb 1, 1989·The British Journal of Psychiatry : the Journal of Mental Science·S E Starkstein, R G Robinson
May 1, 1982·Journal of Gerontology·R I PfefferS Filos
Jan 1, 1982·Journal of Psychiatric Research·J A YesavageV O Leirer
Oct 6, 1997·Psychology and Aging·J BryanJ R Crawford
May 23, 1998·Journal of Neurology, Neurosurgery, and Psychiatry·D R RoyallM Polk
Jan 11, 2000·Stroke; a Journal of Cerebral Circulation·T PohjasvaaraT Erkinjuntti
Jul 4, 2001·Clinical Cornerstone·H Chui
Aug 29, 2001·Neurology·C WentzelI McDowell
May 11, 2002·International Psychogeriatrics·C J VasS Sachdeva
Sep 24, 2002·Arquivos de neuro-psiquiatria·Francisco A C Vale, Stênio J C Miranda
Dec 21, 2002·Acta Neurologica Scandinavica. Supplementum·G C Román
Feb 4, 2003·Arquivos de neuro-psiquiatria·David W Silva, Benito P Damasceno
Aug 30, 2003·Psychological Medicine·C A De JagerM M Budge
Jun 12, 2004·Stroke; a Journal of Cerebral Circulation·Erika Jonsson LaukkaLars Bäckman
Aug 4, 2004·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Kelly Davis GarrettBrian R Ott
Aug 31, 2004·Arquivos de neuro-psiquiatria·Satomi FujiharaAna C Piccolo
Oct 14, 2004·International Journal of Geriatric Psychiatry·S StephensC G Ballard
Jun 26, 2007·Psychological Medicine·D C Steffens, G G Potter
Aug 7, 2007·British Medical Bulletin·J V Bowler
Jan 1, 2007·Dementia & Neuropsychologia·Eliasz EngelhardtJerson Laks
Citations
Sep 7, 2013·Lancet·Adnan I Qureshi, Louis R Caplan
Jul 6, 2014·Neurosurgery Clinics of North America·Mohamed S TelebOsama O Zaidat
Mar 22, 2020·Neuropsychology Review·Prue A WatsonCarmela Pestell
Dec 21, 2018·Arquivos de neuro-psiquiatria·Juliana Conti, Sonia Maria Dozzi Brucki
Nov 3, 2020·Neurocase·Katherine Reiter, Kasia Gustaw Rothenberg
Nov 25, 2020·Neuropsychology Review·Selma LugtmeijerRoy P C Kessels