Neuropsychological profiles of breast cancer and brain tumor cohorts in Northeast Ontario, Canada

Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer
Matias Mariani, Mark William Glister Collins

Abstract

As developments in cancer treatment have improved outcomes, research has increasingly focused on the role of cancer-related cognitive impairment (CRCI) in quality of life for cancer survivors. Impairment profiles have been heterogeneous across studies, necessitating the study of these effects across different cohorts. The purpose of this preliminary study is to compare the memory profiles of Northeast Ontario breast and CNS cancer patients, as there is no literature which exists for profiling CRCI within this largely rural region. Sixty-three outpatients with breast cancer (n = 32) or CNS tumors (n = 30) at the Northeast Cancer Centre in Sudbury, Canada, were administered a neuropsychological test battery as part of their clinical examination. Domains measured within this study included attention and concentration, processing speed, motor function, language skills, verbal and visual memory, and executive functioning. Participants with brain tumors scored poorer on most neuropsychological measures than participants with breast cancer. Initial verbal memory for individuals with breast cancer was lower than delayed recall and recognition trials. Trial 1 performance for this group was also negatively correlated with self-reported a...Continue Reading

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Citations

Feb 15, 2019·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Wedad M HannaSharon Nofech-Mozes

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