NeuroQuery, comprehensive meta-analysis of human brain mapping.

ELife
Jérôme DockèsGaël Varoquaux

Abstract

Reaching a global view of brain organization requires assembling evidence on widely different mental processes and mechanisms. The variety of human neuroscience concepts and terminology poses a fundamental challenge to relating brain imaging results across the scientific literature. Existing meta-analysis methods perform statistical tests on sets of publications associated with a particular concept. Thus, large-scale meta-analyses only tackle single terms that occur frequently. We propose a new paradigm, focusing on prediction rather than inference. Our multivariate model predicts the spatial distribution of neurological observations, given text describing an experiment, cognitive process, or disease. This approach handles text of arbitrary length and terms that are too rare for standard meta-analysis. We capture the relationships and neural correlates of 7547 neuroscience terms across 13 459 neuroimaging publications. The resulting meta-analytic tool, neuroquery.org, can ground hypothesis generation and data-analysis priors on a comprehensive view of published findings on the brain.

References

Mar 1, 1995·NeuroImage·D M Bowden, R F Martin
Aug 10, 2002·NeuroImage·Peter E TurkeltaubThomas A Zeffiro
Jul 28, 2004·NeuroImage·Tor D WagerSusan Reading
May 18, 2005·Neuroinformatics·Angela R LairdPeter T Fox
Jan 13, 2006·Trends in Cognitive Sciences·Russell A Poldrack
Jun 14, 2006·Journal of Cognitive Neuroscience·Colin HumphriesEinat Liebenthal
Feb 3, 2007·Human Brain Mapping·Jack L LancasterPeter T Fox
May 31, 2008·Science·Tom M MitchellMarcel Adam Just
Oct 24, 2008·Neuroinformatics·Daniel GardnerRobert W Williams
Nov 6, 2008·Social Cognitive and Affective Neuroscience·Tor D WagerLauren Kaplan
Jan 27, 2009·NeuroImage·Gholamreza Salimi-KhorshidiThomas E Nichols
Aug 10, 2010·NeuroImage·Thomas NaselarisJack L Gallant
Oct 5, 2010·Trends in Cognitive Sciences·Tal YarkoniTor D Wager
Jun 28, 2011·Nature Methods·Tal YarkoniTor D Wager
Jun 28, 2011·Journal of the American Statistical Association·Jian KangTor D Wager
Oct 17, 2012·PLoS Computational Biology·Russell A PoldrackTal Yarkoni
Apr 11, 2013·Nature Reviews. Neuroscience·Katherine S ButtonMarcus R Munafò
Mar 26, 2014·Psychonomic Bulletin & Review·Steven T Piantadosi
Jul 27, 2014·Journal of Huntington's Disease·Emilia J SitekJulie S Snowden
Sep 25, 2014·Cerebral Cortex·B T Thomas YeoMichael W L Chee
Apr 9, 2015·PLoS Computational Biology·Tor D WagerLisa Feldman Barrett
Sep 24, 2015·Annual Review of Psychology·Russell A Poldrack, Tal Yarkoni
Apr 21, 2016·Proceedings of the National Academy of Sciences of the United States of America·Tor D WagerTal Yarkoni
Jan 6, 2017·Nature Reviews. Neuroscience·Russell A PoldrackTal Yarkoni
Jun 13, 2018·Scientific Data·Ana Luísa PinhoBertrand Thirion
Nov 30, 2018·PLoS Computational Biology·Gaël VaroquauxBertrand Thirion

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Citations

Aug 28, 2020·The European Journal of Neuroscience·Claudio GentiliIoana A Cristea
Mar 5, 2021·Scientific Reports·Mikhail VotinovUte Habel
Mar 27, 2021·Nature Human Behaviour·Justine Y HansenBratislav Misic
Apr 12, 2021·NeuroImage·Keita Suzuki, Okito Yamashita
Apr 19, 2021·Journal of Eating Disorders·Karin FoerdeJoanna E Steinglass
May 14, 2021·Neuropsychology Review·David A CoplandAnthony J Angwin
Aug 27, 2021·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·James K RuffleParashkev Nachev
Oct 16, 2021·Molecular Psychiatry·Francesca MandinoJoanes Grandjean

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Software Mentioned

NeuroSynth Allocation
ALE
Brainmap
scikit
OASIS
NeuroQuery
IBMA
learn
NeuroVault
NeuroSynth

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