PMID: 7024216Jan 1, 1981Paper

Neurotensin-like immunoreactivity in the nervous system of hydra

Histochemistry
C J GrimmelikhuijzenF Sundler

Abstract

Neurotensin-like immunoreactivity is found in nerve fibers present in all body regions of hydra. The nerve fibers are especially numerous in the ectoderm at the bases of the tentacles and in the ectoderm at a site just above the foot. Radioimmunoassays of acetic-acid extracts of hydra, using various region-specific antisera towards mammalian neurotensin, show the presence of multiple neurotensin-related peptides. The amounts of these peptides vary between 1 and 350 pmol per gram wet weight. Gel filtration on Sephadex G-25 reveals a fraction of neurotensin-like peptides that crossreact equally well with an antiserum directed against sequence 1-8 and an antiserum directed against sequence 6-13 of neurotensin. This fraction elutes also at the position of neurotensin and might closely resemble the mammalian peptide. A fraction eluting with the void volume crossreacts preferentially with antisera directed against sequences 1-8 and 10-13 of neurotensin. Several components of apparent lower molecular weight than neurotensin crossreact preferentially with an antiserum against sequence 10-13. These last peptides represent the major portion of the neurotensin-like peptides in hydra.

References

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Citations

Jan 1, 1981·Histochemistry·C J GrimmelikhuijzenN Yanaihara
Jan 1, 1982·Histochemistry·C J GrimmelikhuijzenL P Schot
Jan 1, 1981·Histochemistry·C J GrimmelikhuijzenF Sundler
Aug 1, 1983·Neuroscience·C J Grimmelikhuijzen
Jan 1, 1984·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·G VenturiniV Margotta
Jan 1, 1988·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·G B Stefano
Jan 1, 1988·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·P F Basch, B C Gupta
Nov 15, 2006·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·G Kass-Simon, Paola Pierobon
Jan 1, 1982·Annals of the New York Academy of Sciences·F SundlerR Uddman
Feb 4, 1994·Brain Research·J AmmermüllerU Janssen-Bienhold
Jan 1, 1993·Acta Oto-laryngologica. Supplementum·Y HosodaT Kumazawa
Sep 9, 1996·The Journal of Comparative Neurology·M SakaguchiY Kobayakawa
Feb 20, 2015·The Journal of Experimental Biology·Stefan Gründer, Marc Assmann

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