Neurotensin neurons in the rat hypothalamus: an immunocytochemical study

Endocrinology
D KahnS E Leeman

Abstract

Neurotensin was localized in the hypothalamic tissues of adult Sprague-Dawley rats by immunoperoxidase techniques. Visualization of perikarya was greatly enhanced by intraventricular administration of colchicine. Many perikarya containing neurotensin-like immunoreactivity were seen in the medial preoptic area, the periventricular hypothalamus, the parvocellular portion of the paraventricular nucleus, the arcuate nucleus, and the lateral hypothalamus in the perifornical area. There were moderate numbers of cell bodies in the ventral portion of the anterior hypothalamus, the dorsomedial nucleus, and the posterior hypothalamus. No positive cells were seen in the suprachiasmatic, ventromedial, or mammillary nuclei. Reactive fibers were generally distributed in the same regions as cell bodies. Additional dense collections were seen in the lateral part of the zona externa of the median eminence, the pituitary stalk, the posterior mammillary nucleus, and the most lateral portions of the hypothalamus at the medial edge of the crura cerbri. There were smaller numbers of fibers found in the pre-mammillary and posterior hypothalamic nuclei and the posterior pituitary gland. These results indicate that the neurotensin system in the hypotha...Continue Reading

Citations

Dec 1, 1984·Italian Journal of Neurological Sciences·A Albanese, M C Altavista
Sep 22, 1987·Brain Research·D J Eckland, S L Lightman
Jan 1, 1993·Life Sciences·R IbañezC Dieguez
Jan 1, 1996·Neuroscience and Biobehavioral Reviews·L L Bernardis, L L Bellinger
Jan 1, 1983·Pharmacology & Therapeutics·G P KozlowskiE A Zimmerman
Feb 1, 1995·Brain Research. Brain Research Reviews·T A LantosM Palkovits
Mar 1, 1991·Peptides·M De LeónS González-Barón
Jan 1, 1989·Progress in Neurobiology·N Ben-JonathanJ F Hyde
Jan 1, 1981·Brain Research Bulletin·A J SilvermanE A Zimmerman

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