Neurotensin regulation of TSH secretion in the rat

Biochemical and Biophysical Research Communications
M C SheppardD B Ramsden

Abstract

Tri-iodothyronine stimulates neurotensin secretion from rat hypothalami in vitro. Propylthiouracil treatment of rats is associated with a decrease in anterior pituitary neurotensin content, an increase in hypothalamic content and an impaired release of peptide from hypothalami in vitro. In addition neurotensin has a direct inhibitory effect on TRH-stimulated TSH release from anterior pituitary in vitro. These observations suggest a physiological role for neurotensin in the control of TSH secretion in the rat.

References

Dec 15, 1976·Life Sciences·G R Uhl, S H Snyder
Mar 1, 1979·European Journal of Pharmacology·A J OsbahrA J Prange
Mar 1, 1978·The Journal of Endocrinology·P E BelchetzR L Himsworth
Nov 1, 1979·The Journal of Endocrinology·A M Blackburn, S R Bloom
Jan 1, 1969·Neuroendocrinology·A Kajihara, J W Kendall
Jan 1, 1971·Neuroendocrinology·W F Chambers, R J Sobel
Jul 8, 1982·Nature·M GoedertP C Emson
Nov 1, 1982·The Journal of Endocrinology·S G Daniel, D B Ramsden

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Citations

Apr 18, 2003·Thyroid : Official Journal of the American Thyroid Association·Carmen C Pazos-MouraEgberto Gaspar de Moura
Jun 1, 1990·Clinical and Experimental Pharmacology & Physiology·S D Kivlighn, B S Jandhyala
Dec 28, 2006·CNS Drugs·Mona BoulesElliott Richelson
Aug 3, 2006·Peptides·Mona BoulesElliott Richelson
Apr 1, 1997·Frontiers in Neuroendocrinology·W H Rostène, M J Alexander
Nov 26, 1998·Journal of Pediatric Endocrinology & Metabolism : JPEM·M BozzolaR M Schimpff
Dec 22, 2004·Arquivos brasileiros de endocrinologia e metabologia·Egberto G de Moura, Carmen C Pazos de Moura
Oct 1, 1993·Journal of Endocrinological Investigation·R Toni, R M Lechan

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