PMID: 490191Aug 1, 1979Paper

Neurotoxic destruction of the serotoninergic innervation of the rat subcommissural organ is followed by reinnervation through collateral sprouting of non-monoaminergic neurons

Journal of Neurocytology
L Wiklund, K Møllgård

Abstract

Specific neurotoxic destruction of the serotoninergic innervation of the subcommissural organ of the rat is followed by an efficient reinnervation by collateral sprouting of non-monoaminergic axons, which normally do not innervate the SCO cells. Morphologically, the reinnervating fibres totally replace the serotoninergic synapses lost by the lesion, but, functionally, they fail to substitute for the potent inhibitory control of secretory activity normally exerted by the serotoninergic innervation. It is possible that the observed reinnervation by foreign synapses explains why the regrowing serotoninergic neurons fail to re-establish their connections with the SCO.

References

Jun 12, 1978·Annals of the New York Academy of Sciences·L WiklundA Nobin
Aug 1, 1979·Journal of Neurocytology·K Møllgård, L Wiklund
Jun 9, 1975·Cell and Tissue Research·J E Kimble, K Mollagård
Apr 15, 1973·Life Sciences. Pt. 1: Physiology and Pharmacology·H G BaumgartenE Rosengren
Jan 1, 1973·Brain, Behavior and Evolution·D C GoodmanJ A Horel
Jun 1, 1969·Brain Research·G Raisman
Jan 1, 1964·International Review of Neurobiology·C D CLEMENTE

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Citations

Aug 1, 1979·Journal of Neurocytology·K Møllgård, L Wiklund
Apr 8, 1985·Brain Research·R Ferres-TorresJ Ramos-Navarro
Feb 1, 1988·The International Journal of Neuroscience·J A Jesberger, J S Richardson
Jan 1, 1989·Virchows Archiv. B, Cell Pathology Including Molecular Pathology·A Schmitt-GräffG Gabbiani
Feb 15, 1985·Experientia·M F Seifert, S C Marks
Mar 10, 2001·Microscopy Research and Technique·A J JiménezJ M Pérez-Fígares
Nov 1, 1982·The Journal of Comparative Neurology·K Kalil, T Reh

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