Neurotoxins from snake venom

Annales Françaises D'anesthèsie Et De Rèanimation
S LarréchéM Goyffon

Abstract

Many snakes are able to quickly immobilize prey, thanks to their venom neurotoxins. Most of these snakes belong to families Elapidae or Hydrophidae but neurotoxins were also isolated from families Viperidae and Colubridae. Ophidian neurotoxins can be classified into several categories: neurotoxins which inhibit synaptic transmission (postsynaptic and presynaptic neurotoxins) and neurotoxins which facilitate it excessively (dendrotoxin and fasciculin). Their toxicity is dose-dependent, and venom effects are extremely fast. The clinical feature is a potentially fatal neurological syndrome, the so called cobraic syndrome. Because death by respiratory arrest may occur quickly with cobraic syndrome, immunotherapy is a true emergency, because toxins irreversible fixing makes immunotherapy effect uncertain after a few hours passed.

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Sep 12, 2007·Anaesthesia·S LarréchéM Goyffon

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Citations

Mar 20, 2009·Annales Françaises D'anesthèsie Et De Rèanimation·A MoujahidL Safi
Apr 22, 2008·Annales Françaises D'anesthèsie Et De Rèanimation·M ChaniG Mion
Oct 4, 2011·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·I ClaudetE Grouteau
Jun 30, 2012·Pediatric Emergency Care·Isabelle ClaudetErick Grouteau
Jan 29, 2016·Biologie aujourd'hui·Max GoyffonGrazyna Faure

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