Neurotransmitter release changes induced by low power 830 nm diode laser irradiation on the neuromuscular junctions of the mouse

Lasers in Surgery and Medicine
Renata Amadei NicolauJosep Tomàs

Abstract

Treating patients with a Gallium-Aluminum-Arsenide (GaAlAs) infrared (IR) diode laser reduces muscle spasm and increases mobility in the muscles. The effect of low intensity laser irradiation on nerve function, growth, and repair mechanisms is a contentious area of research. We have addressed one aspect of this controversy by systematically examining the influence of 830 nm laser radiation on neurotransmitter release in neuromuscular junctions (NMJ) of the mouse diaphragm. Thirty adult mice were studied. Diode laser GaAlAs 830 nm (4 and 12 J/cm2) was used. Neurotransmitter release was studied by conventional intracellular recording techniques on curarized muscles or high magnesium media. The quantal content, amplitude, and latency of the end-plate potentials (EPPs) were analyzed. Frequency and amplitude were evaluated for the miniature end-plate potentials (MEPPs). Facilitation of the neurotransmitter release was also evaluated by paired pulse stimulation. The irradiated (12 J/cm2) muscles showed a significant reduction in quantal content (P = 0.01) and EPP amplitude (P = 0.04), but the latency, spontaneous transmitter release (MEPPs) and paired pulse facilitation did not change. No alterations were observed in NMJ irradiated w...Continue Reading

References

Sep 15, 1992·Journal of Photochemistry and Photobiology. B, Biology·R LubartH Breitbart
Aug 1, 1985·Physical Therapy·D G GreathouseR L Gilmore
May 1, 1970·The Journal of Physiology·B Katz, R Miledi
Feb 1, 1981·The Journal of Physiology·E M McLachlan, A R Martin
Jan 1, 1995·Lasers in Surgery and Medicine·J R Basford
Jan 1, 1996·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·S M KhullarH R Haanaes
Jul 1, 1996·Journal of Photochemistry and Photobiology. B, Biology·H BreitbartR Lubart
Jan 22, 1998·The American Journal of Physiology·A Losavio, S Muchnik
Apr 1, 1999·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·K Branco, M A Naeser
Jun 12, 1999·Journal of Photochemistry and Photobiology. B, Biology·T Karu
Jan 12, 2000·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·M Miloro, M Repasky
Jan 5, 2002·Journal of Clinical Laser Medicine & Surgery·J G NobleG D Baxter
Mar 14, 2002·Lasers in Surgery and Medicine·Ulku ComelekogluCanan Erdogan
Mar 28, 2003·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Eleni AlexandratouSpyros Loukas
Mar 17, 2004·Lasers in Surgery and Medicine·Renata Amadei NicolauJosep Tomàs

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Citations

Aug 3, 2010·Current Pain and Headache Reports·Mario F P Peres, Giancarlo Lucchetti
Oct 22, 2010·Photomedicine and Laser Surgery·Carlos A KelenczRenata A Nicolau
Jul 23, 2008·Photochemistry and Photobiology·Rosany Doin-SilvaMaria Alice da Cruz-Höfling
Nov 16, 2013·Lasers in Medical Science·Kenichi KumazakiHideki Kawai
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Nov 30, 2013·Lasers in Medical Science·Thiago dos Santos MacielAlderico Rodrigues de Paula Júnior
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Sep 18, 2008·Lasers in Surgery and Medicine·Mitsuaki KomatsuKazuhiro Watanabe
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Jun 15, 2016·Lasers in Medical Science·Marcele Florêncio das NevesMário Oliveira Lima
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