Neurotrophic factors and neuro-muscular disease: II. GDNF, other neurotrophic factors, and future directions

Muscle & Nerve
Hiroshi Mitsumoto, K Tsuzaka

Abstract

This is the second of two reviews in which we discuss the essential aspects of neurotrophic factor neurobiology, the characteristics of each neurotrophic factor, and their clinical relevance to neuromuscular diseases. The previous paper reviewed the neurotrophin family and neuropoietic cytokines. In the present article, we focus on the GDNF family and other neurotrophic factors and then consider future approaches that may be utilized in neurotrophic factor treatment.

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Related Concepts

Myopathy
GDNF gene
Neurotrophic factor
BDNF gene
Neurotrophin Binding
Neurite Outgrowth Factors
Muscular Atrophy
Neurobiology
Neuromuscular Diseases
Cytokine

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