Neutral polyfluorinated compounds in indoor air in Germany--the LUPE 4 study

Chemosphere
Hermann FrommeWolfgang Völkel

Abstract

Perfluoroalkyl- and polyfluoroalkyl-substances (PFAS) have been detected in many types of environmental media and biota including humans. We determined volatile PFAS, including fluorotelomer alcohols (FTOHs), fluorotelomer acrylates (FTACs), perfluorooctane sulfonamides (FOSAs), and perfluorooctane sulfonamidoethanols (FOSEs), in indoor air of residences and schools in Germany. FTOHs, FTACs, FOSEs, and FOSAs were quantified with median levels in schools (in residences) of 11,783pg/m(3) (13,198pg/m(3)), 737pg/m(3) (450pg/m(3)), 130pg/m(3) (278pg/m(3)), and 243pg/m(3) (110pg/m(3)), respectively. Using our data and previously published results in a simplified model based on the medians and 95th percentiles, the "typical" and "high" daily non-dietary exposures were calculated to be 4.2ng/kg body weight (9.9ng/kgb.w.) for Σ-FTOHs and 0.1ng/kgb.w. (0.8ng/kgb.w.) for Σ-FOSEs/FOSAs in children. Inhalation was the dominant intake pathway for FTOHs; however, dust ingestion contributed significantly to the total intake of FOSEs/FOSAs. In organisms, 8:2 FTOH is degraded to perfluorooctanoate (PFOA). Assuming that 1% of 8:2 FTOH is converted to PFOA, 8:2 FTOH exposure in Germany has a negligible contribution to the total daily PFOA exposure...Continue Reading

References

Jun 24, 2004·Environmental Science & Technology·Mary Joyce A DinglasanScott A Mabury
Jul 21, 2004·Environmental Science & Technology·David A EllisTimothy J Wallington
May 4, 2005·Drug and Chemical Toxicology·Gregory S LadicsRobert C Buck
May 4, 2005·Drug and Chemical Toxicology·Eve MylchreestJudith C Stadler
May 13, 2005·Toxicological Sciences : an Official Journal of the Society of Toxicology·Naomi KudoYoichi Kawashima
Jul 30, 2005·Drug and Chemical Toxicology·E MylchreestG L Kennedy
Aug 16, 2005·Chemico-biological Interactions·Jonathan W MartinPeter J O'Brien
Mar 18, 2006·Toxicological Sciences : an Official Journal of the Society of Toxicology·William J FasanoRaymond A Kemper
Jun 8, 2007·Journal of Environmental Monitoring : JEM·Jonathan L BarberKevin C Jones
Dec 14, 2007·Environmental Science & Technology·Hermann FrommeDorothee Twardella
Mar 12, 2008·Drug and Chemical Toxicology·Gregory S LadicsSeiji Shin-Ya
Apr 19, 2008·Risk Analysis : an Official Publication of the Society for Risk Analysis·David TrudelKonrad Hungerbühler
Jun 21, 2008·International Journal of Hygiene and Environmental Health·Hermann FrommeDorothee Twardella
Oct 12, 2010·Environmental Science & Technology·Vera LangerRalf Ebinghaus
May 20, 2011·Journal of Agricultural and Food Chemistry·Cornelle W NoorlanderMarco J Zeilmaker
Mar 14, 2012·International Journal of Hygiene and Environmental Health·André ConradDavid Groneberg
Sep 29, 2012·Environment International·Robin VestergrenIan T Cousins
Oct 24, 2012·Chemosphere·Wanyang LiuAkio Koizumi
Nov 10, 2012·Environment International·Helena NilssonHåkan Westberg
May 9, 2013·Environment International·Martin SchlummerJosef Müller
Oct 12, 2013·Environmental Toxicology and Chemistry·Craig M ButtScott A Mabury
Mar 1, 2014·Toxicology·Tessa SerexScott E Loveless
Sep 3, 2014·Chemosphere·Mark H RussellRobert C Buck
Apr 10, 2015·Environmental Science and Pollution Research International·Matthias KotthoffDominik Fiedler

❮ Previous
Next ❯

Citations

Mar 7, 2020·Environmental Science. Processes & Impacts·Clara M A Eichler, John C Little
Dec 13, 2018·EFSA Journal·UNKNOWN EFSA Panel on Contaminants in the Food Chain (CONTAM)Tanja Schwerdtle
Nov 25, 2018·Journal of Exposure Science & Environmental Epidemiology·Elsie M SunderlandJoseph G Allen
Jun 2, 2020·Human Reproduction Update·Ning DingSung Kyun Park
Oct 1, 2020·EFSA Journal·UNKNOWN EFSA Panel on Contaminants in the Food Chain (EFSA CONTAM Panel)Tanja Schwerdtle
Nov 9, 2019·Environmental Science & Technology·Stuart HarradAnn-Marie Coggins

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.