PMID: 2489087Aug 1, 1989Paper

Neutron fibre diffraction study of DNA hydration

International Journal of Biological Macromolecules
V T ForsythS A Mason

Abstract

Interactions with water are crucial to the conformation assumed by the DNA double helix. The location of water around the D conformation has been investigated in a neutron fibre diffraction study which shows that water is ordered in the minor groove of the DNA. The D conformation is important since its occurrence is limited to specific DNA base pair sequences which have been identified as functionally significant. This study is of particular interest because the D conformation has not been reported in single crystal studies of oligonucleotides.

References

Mar 11, 1983·Nucleic Acids Research·S ArnottR L Ratliff
Aug 25, 1983·Journal of Molecular Biology·A MahendrasingamJ Vergne
Mar 18, 1982·Nature·N J RhodesR A Warren
Sep 25, 1981·Journal of Molecular Biology·H R Drew, R E Dickerson
Feb 21, 1980·Nature·S ArnottR L Ratliff
Oct 15, 1980·Journal of Molecular Biology·A G LeslieR L Ratliff
Apr 25, 1953·Nature·M H F WILKINSH R WILSON
Apr 25, 1953·Nature·R E FRANKLIN, R G GOSLING

❮ Previous
Next ❯

Citations

Aug 13, 2004·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Watson FullerArumugam Mahendrasingam
Mar 4, 2009·Acta Crystallographica. Section F, Structural Biology and Crystallization Communications·Ricardo M F LealV Trevor Forsyth
Mar 12, 2011·Acta Crystallographica. Section F, Structural Biology and Crystallization Communications·Sarah M TiggelaarV Trevor Forsyth
Mar 31, 2015·Journal of Molecular Biology·Christian Edlich-MuthErnest D Laue
Feb 27, 1999·Journal of Molecular Biology·M Feig, B M Pettitt
Nov 14, 2014·Journal of the American Chemical Society·James P HallChristine J Cardin
Dec 1, 1994·Physical Review. E, Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics·G Hummer, D M Soumpasis
Dec 1, 1992·Journal of Biomolecular Structure & Dynamics·P LanganW Fuller
Aug 25, 2006·The Journal of Physical Chemistry. B·Jana Chocholousová, Michael Feig

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.