Neutropenia, thrombocytopenia and hepatic injury associated with dexketoprofen trometamol therapy in a previously healthy 35-year-old woman

Journal of Clinical Pharmacy and Therapeutics
S ZabalaL Mouronval

Abstract

This case report describes a previously healthy 35-year-old woman, with an episode of fever, neutropenia, thrombocytopenia and elevation of biochemical markers of liver injury, 10 days after beginning drug therapy with dexketoprofen trometamol. Infectious and autoimmune causes of neutropenia, and viral or autoimmune hepatitis were excluded. The resolution following withdrawal of dexketoprofen trometamol confirms the possibility of an adverse drug reaction.

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Citations

Dec 6, 2008·World Journal of Gastroenterology : WJG·Kazuto Tajiri, Yukihiro Shimizu
Sep 1, 2011·Pain Management·Jean-Sébastien Walczak
Jul 15, 2015·Enfermedades infecciosas y microbiología clínica·Judith Álvarez OteroJavier de la Fuente Aguado
Nov 22, 2014·Wiener klinische Wochenschrift·Sehmus OlmezAlpaslan Yavuz
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Mar 3, 2011·The Annals of Pharmacotherapy·Giuseppe FamularoGiovanni Minisola
Jul 28, 2018·Drug and Chemical Toxicology·Merve Kılıc, Berrin Ayaz Tuylu
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Nov 7, 2008·Expert Review of Neurotherapeutics·Manuel J Barbanoj RodríguezSalvador Rico Amaro

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