PMID: 7542381Apr 1, 1995Paper

Neutrophil and monocyte beta 2-integrin expression in trisomic fetuses

Prenatal Diagnosis
G MakrydimasK H Nicolaides

Abstract

Flow cytometry was used to measure neutrophil and monocyte beta 2-integrin expression in fetuses with trisomy 18 (n = 7) and trisomy 21 (n = 7) at 20-25 weeks' gestation. The values were compared with those of 112 chromosomally normal fetuses. There were no significant differences in beta 2-integrin expression between normal and aneuploid fetuses. These findings demonstrate that in trisomies 21 and 18, alteration in beta 2-integrin expression is unlikely to contribute to the pathogenesis of immunological deficiencies that have been observed in these aneuploidies both prenatally and postnatally.

References

Apr 27, 1992·Journal of Immunological Methods·M G MaceyA C Newland
Jan 1, 1995·American Journal of Obstetrics and Gynecology·B ThilaganathanK H Nicolaides
Apr 1, 1994·Prenatal Diagnosis·G MakrydimasK H Nicolaides
Jan 1, 1993·British Journal of Obstetrics and Gynaecology·B ThilaganathanK Nicolaides
Jan 1, 1993·Archives of Disease in Childhood·A Finn

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Related Feeds

Adhesion Molecules in Health and Disease

Cell adhesion molecules are a subset of cell adhesion proteins located on the cell surface involved in binding with other cells or with the extracellular matrix in the process called cell adhesion. In essence, cell adhesion molecules help cells stick to each other and to their surroundings. Cell adhesion is a crucial component in maintaining tissue structure and function. Discover the latest research on adhesion molecule and their role in health and disease here.