PMID: 8613562Dec 1, 1995Paper

Neutrophil elastase in crevicular fluid: comparison of a middle-aged general population with healthy and periodontitis groups

Journal of Clinical Periodontology
Q T SmithG Fischer

Abstract

Neutrophil elastase (NE) was measured in crevicular fluid (GCF) collected from 3 subject groups. GCF was harvested at a single visit of subjects with periodontal health (n = 21) and with periodontitis (n = 28). Samples were obtained from 132 middle-aged, middle-class health conscious patients of a health maintenance organization (HMO) at baseline and 1 year later. GCF NE was higher in periodontitis than in health. Mean GCF NE of HMO subjects was much closer to health than to periodontitis. Few members of the HMO population had enzyme levels typical of periodontitis. Subjects and sites of the HMO population were segregated into 3 categories based on enzyme levels of the healthy and periodontitis subjects. Most HMO subjects and sites were in the activity category corresponding to healthy subjects. Only a small portion were in the activity category common in periodontitis. Enzyme levels in the highest activity category at both samplings were infrequent. High enzyme levels in the HMO population were not associated with attachment loss. Thus, assay of GCF NE provided little evidence of disease in a middle-aged, middle-class health conscious general population. This finding confirms an analysis of epidemiological surveys which conclu...Continue Reading

References

Sep 1, 1992·Journal of Periodontal Research·Q T SmithJ L Stoltenberg
Apr 1, 1992·Journal of Periodontology·K G PalcanisM K Jeffcoat
Dec 1, 1991·Journal of Periodontology·C W Douglass, C H Fox
Mar 1, 1991·Journal of Clinical Periodontology·Q T Smith, S J Geegan
Jan 1, 1986·Journal of Clinical Periodontology·L Sandholm
May 1, 1986·Journal of Clinical Periodontology·D H Fine, I D Mandel
Jan 1, 1970·Journal of Periodontal Research·R Attström
Sep 1, 1984·Journal of Periodontal Research·C ThurreP Baehni
Feb 1, 1994·Journal of Periodontology·G C ArmitageT J Sharp
Dec 1, 1963·Acta Odontologica Scandinavica·H LOE, J SILNESS

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Citations

Jan 6, 2001·Journal of Clinical Periodontology·J M HerrmannJ Meyle
Aug 29, 1998·Journal of Clinical Periodontology·S J FokkemaH H Renggli
Sep 30, 2003·Journal of Periodontology·Gary C Armitage, UNKNOWN Research, Science and Therapy Committee of the American Academy of Periodontology
Jan 24, 2014·TheScientificWorldJournal·Carlo CafieroGilberto Sammartino
Dec 3, 2014·Immunology Letters·Massimo Costalonga, Mark C Herzberg
Jun 15, 2007·Journal of Periodontal Research·Y UjiieM Fukae
Aug 1, 2003·Journal of Periodontology·UNKNOWN Research, Science and Therapy Committee
May 1, 2021·Journal of Clinical Medicine·Carlo CafieroStefania Leuci

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