Mar 27, 1976

Neutrophil pyruvate kinase deficiency with recurrent staphylococcal infections: first reported case

British Medical Journal
P S BurgeA R Hayward


A woman with an intracellular killing defect in the neutrophils had neutrophil pyruvate kinase deficiency. She had had recurrent staphylococcal infections throughout her life. The enzyme present was unstable and its kinetics were abnormal.

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Mentioned in this Paper

Neutrophil Band Cells
Deficiency of Pyruvate Kinase
Phagocyte Bactericidal Dysfunction
Neutrophils as Percentage of Blood Leukocytes (Lab Test)
Thyroid Hormone Plasma Membrane Transport Defect
Staphylococcal Infections
Absolute Neutrophil Count
Adenosine Triphosphate, Elevated, Of Erythrocytes
R-Type Pyruvate Kinase

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